Comments on: A major step toward an Alzheimer’s treatment and vaccine

By: George Holizki

George Holizki — Sun, 31 Mar 2013 17:41:00 +0000

My wife has Alzheimer’s. I am sure she would be willing to be involved in test trials to get rid of Alzheimer’s. It is not nice to see her go from being a Canadian Ladies’ Championship golfer (twice) to one who can hardly speak and is bed ridden. I certainjly would support any attempt to help Vivian get rid of Alzheimer’s. Let me know if this can happen. Thanks.

By: Aaron Wright

Aaron Wright — Sun, 20 Jan 2013 18:30:42 +0000

This is an exciting breakthrough. Alzheimer’s is such a terrible disease, and I would argue that the need for a treatment ranks right up there with cancer and HIV. To watch someone’s mind slowly degrade over so many years is aweful.

By: G. Ward

G. Ward — Fri, 18 Jan 2013 15:59:51 +0000

I have Alzheimers history in my father’s line and am, of course, interested in any significant progress in treatment for this disease.

By: Bri

Bri — Thu, 17 Jan 2013 21:43:23 +0000

It’s comforting to know that substantial progress is being made. For the most part these type treatments are as a preventative. Once damage has occured to the neurons, other therapies will be needed foreshore full functioning.

By: asiwel

asiwel — Thu, 17 Jan 2013 20:55:06 +0000

This sounds like good research and is published in PNAS, But I thought much work had been done already on toll-like receptor 4 and on MPL. I understood from popularizations of other research that simply removing amyloid beta plaques had not shown the good results that had been hoped for. Here, apparently, these mice did show improvement in cognitive function. Since GlaxoSmithKline has used this as a vaccine adjuvant, I wonder if there are studies of the rate and severity of Alzheimers in populations who have received this adjuvant and those that have not? It is simply hard to put a report like this into the larger context of research progress … without reading their literature review, I guess.

By: Chis

Chis — Thu, 17 Jan 2013 20:50:10 +0000

Sounds great! Sign me up also.

By: McTruck

McTruck — Thu, 17 Jan 2013 19:12:19 +0000

I’ll take my dose now.

By: Chris

Chris — Thu, 17 Jan 2013 18:00:02 +0000

Amazing!