Comments on: A roadmap for metabolic reprogramming of aging

By: NakedApe

NakedApe — Sun, 23 Dec 2012 12:05:29 +0000

One thing I don’t understand — if resveratrol is found in the skins of red grapes, then why don’t people just eat red grapes instead of drinking red wine? Can somebody explain this to me? The alcohol would seem to counteract any benefits of drinking red wine, to my mind.

By: Vin

Vin — Thu, 06 Dec 2012 00:06:13 +0000

How can it be determined if this hippocampus shrinkage is due to increased efficiency of function requiring less tissue to be supported?

By: Damon Montano

Damon Montano — Wed, 05 Dec 2012 01:54:45 +0000

We want to live forever already. The clock is ticking….

By: GatorALLin

GatorALLin — Wed, 05 Dec 2012 00:38:05 +0000

good point… ( a huge difference of not dying early from cancer or other problems, vs extending max lifespan).

http://online.wsj.com/article/SB10000872396390444772804577619394017185860.html

By: GatorALLin

GatorALLin — Wed, 05 Dec 2012 00:35:40 +0000

You might need a few hundred glasses of red wine to get the benefits you need… that and drinking has some real negative consequences also.

http://www.dailymail.co.uk/health/article-535988/Wine-worse-brain-beer-scientists-reveal-blow-women-drinkers.html

Drinking wine damages the brain more than beer or spirits, scientists claim.
They say it particularly affects the hippocampus, the part of the brain associated with memory and spatial awareness, and one of the first areas to be affected by Alzheimer’s disease.

Read more: http://www.dailymail.co.uk/health/article-535988/Wine-worse-brain-beer-scientists-reveal-blow-women-drinkers.html#ixzz2E8JgILcP
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They found the hippocampus, which is located deep within the brain’s temporal lobes, was up to 10 per cent smaller in those who drank
The team of psychiatrists behind the study said: “This is the first study investigating the impact of the type of preferred beverage on brain-volume shrinkage in patients with alcohol dependence.”
The study compared brain scans from diagnosed alcoholics with those from healthy adults. In non-alcoholics the hippocampus was 3.85ml.
In beer drinkers it was 3.4ml, in spirit drinkers 2.9ml and for wine drinkers it was the smallest, just 2.8ml. The hippocampus is located deep within the brain’s temporal lobes and is also one of the first areas of the brain to be affected by Alzheimer’s disease. Memory, navigation and spatial awareness can all be affected, and it can also cause feelings of disorientation.

By: Bri

Bri — Tue, 04 Dec 2012 22:32:10 +0000

I’m pretty shure your near the finger lakes. Some mighty fine wine around there!

By: vaidy.bala@yahoo.ca

vaidy.bala@yahoo.ca — Tue, 04 Dec 2012 22:32:01 +0000

Calories restriction in Diabetics is already proven to help in the management of blood sugar. This is to be noted.

By: Laura C.

Laura C. — Tue, 04 Dec 2012 17:34:27 +0000

Just a minor point — I believe the primate studies did NOT show longevity increase from calorie restriction, though as a side finding they did confirm that everyone benefits from cutting carbs from the diet.

By: Gorden Russell

Gorden Russell — Tue, 04 Dec 2012 15:37:34 +0000

Taking pills is no fun, I’d rather just drink a few glasses of wine (or three or four glasses (or five or six)).

By: JohnWayne

JohnWayne — Tue, 04 Dec 2012 14:33:45 +0000

this one? http://longevinex.com/

By: melajara

melajara — Tue, 04 Dec 2012 12:30:22 +0000

Summarizing: to have SIRT3 better activated, don’t forget your daily pill of Resveratrol, LOL