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	<title>Comments on: Breakthrough: compound generated by low carb/low-calorie diet blocks effects of aging</title>
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	<description>Accelerating Intelligence</description>
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		<title>By: Cynhtia</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-93286</link>
		<dc:creator>Cynhtia</dc:creator>
		<pubDate>Tue, 29 Jan 2013 06:02:27 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-93286</guid>
		<description>Looks like Beth nailed it dead on.  People don&#039;t want to do it the hard way, they want the &quot;where&#039;s the pill form of this?&quot;  kind of crap.  We as a nation need to STOP the ridiculous indulgences all the time.  If we all went even by a 90%/10% rule of eating right/indulgence - we&#039;d all be healthy as could be.  Throw in daily exercise and we wouldn&#039;t know what to do with ourselves.</description>
		<content:encoded><![CDATA[<p>Looks like Beth nailed it dead on.  People don&#8217;t want to do it the hard way, they want the &#8220;where&#8217;s the pill form of this?&#8221;  kind of crap.  We as a nation need to STOP the ridiculous indulgences all the time.  If we all went even by a 90%/10% rule of eating right/indulgence &#8211; we&#8217;d all be healthy as could be.  Throw in daily exercise and we wouldn&#8217;t know what to do with ourselves.</p>
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		<title>By: Ian</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-70148</link>
		<dc:creator>Ian</dc:creator>
		<pubDate>Fri, 14 Dec 2012 16:08:07 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-70148</guid>
		<description>Where is the pill form of this?</description>
		<content:encoded><![CDATA[<p>Where is the pill form of this?</p>
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		<title>By: Dayle</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-70108</link>
		<dc:creator>Dayle</dc:creator>
		<pubDate>Fri, 14 Dec 2012 15:16:56 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-70108</guid>
		<description>Well only a few opinions on diet.  How about follow one simple rule: less is better, all things in moderation. Get daily exercise....I&#039;m done</description>
		<content:encoded><![CDATA[<p>Well only a few opinions on diet.  How about follow one simple rule: less is better, all things in moderation. Get daily exercise&#8230;.I&#8217;m done</p>
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		<title>By: Makko</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-68278</link>
		<dc:creator>Makko</dc:creator>
		<pubDate>Wed, 12 Dec 2012 18:10:35 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-68278</guid>
		<description>Totally not what they&#039;re saying...

It&#039;s calorie restriction over a prolonged period of time. Not a day or week.</description>
		<content:encoded><![CDATA[<p>Totally not what they&#8217;re saying&#8230;</p>
<p>It&#8217;s calorie restriction over a prolonged period of time. Not a day or week.</p>
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		<title>By: Havelock Vetinari</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-68089</link>
		<dc:creator>Havelock Vetinari</dc:creator>
		<pubDate>Wed, 12 Dec 2012 12:02:44 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-68089</guid>
		<description>Ketone bodies such as βOHB are produced as a by-product of lipolysis, which is only possible when insulin levels are low (and therefore only when blood glucose is low).  Skipping a meal a day is unlikely to result in any significant ketosis.</description>
		<content:encoded><![CDATA[<p>Ketone bodies such as βOHB are produced as a by-product of lipolysis, which is only possible when insulin levels are low (and therefore only when blood glucose is low).  Skipping a meal a day is unlikely to result in any significant ketosis.</p>
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		<title>By: Fred Hahn</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-67637</link>
		<dc:creator>Fred Hahn</dc:creator>
		<pubDate>Tue, 11 Dec 2012 20:57:27 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-67637</guid>
		<description>If you eat low carb and put yourself into a state of nutritional ketosis, you don&#039;t have to keep calories low to derive the benefits. Check out the research by Jeff Volek, Richard Feinman and Stephen Phinney.</description>
		<content:encoded><![CDATA[<p>If you eat low carb and put yourself into a state of nutritional ketosis, you don&#8217;t have to keep calories low to derive the benefits. Check out the research by Jeff Volek, Richard Feinman and Stephen Phinney.</p>
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		<title>By: dv</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-67535</link>
		<dc:creator>dv</dc:creator>
		<pubDate>Tue, 11 Dec 2012 17:14:27 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-67535</guid>
		<description>Research into CRON (calorie-restriction, optimal nutrition) and longevity suggests that the caloric-restriction can happen any number of ways, just so long as it happens. Skpping one meal per day is essentially the same as eating normally then fasting for one day per week, for example. Fasting for an entire week once or twice per year might yield similar results, but the method is likely unnecessary when there are simpler alternatives. There are adverse health effects with extended fasting, but week-long fasting (e.g., Ramadan) have been long practiced and do not seem tied to adverse health effects, but there is a reason these are performed only annually: most people find the activity restrictive or unpleasant; hence the tie to a spiritual rite.</description>
		<content:encoded><![CDATA[<p>Research into CRON (calorie-restriction, optimal nutrition) and longevity suggests that the caloric-restriction can happen any number of ways, just so long as it happens. Skpping one meal per day is essentially the same as eating normally then fasting for one day per week, for example. Fasting for an entire week once or twice per year might yield similar results, but the method is likely unnecessary when there are simpler alternatives. There are adverse health effects with extended fasting, but week-long fasting (e.g., Ramadan) have been long practiced and do not seem tied to adverse health effects, but there is a reason these are performed only annually: most people find the activity restrictive or unpleasant; hence the tie to a spiritual rite.</p>
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		<title>By: brian</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-67366</link>
		<dc:creator>brian</dc:creator>
		<pubDate>Tue, 11 Dec 2012 11:18:18 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-67366</guid>
		<description>Isn&#039;t this atkins in a different format?</description>
		<content:encoded><![CDATA[<p>Isn&#8217;t this atkins in a different format?</p>
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		<title>By: Damon Montano</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-67176</link>
		<dc:creator>Damon Montano</dc:creator>
		<pubDate>Tue, 11 Dec 2012 06:10:30 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-67176</guid>
		<description>Starvation diet here I come again.</description>
		<content:encoded><![CDATA[<p>Starvation diet here I come again.</p>
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		<title>By: Shane</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-67171</link>
		<dc:creator>Shane</dc:creator>
		<pubDate>Tue, 11 Dec 2012 06:06:25 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-67171</guid>
		<description>Hey Frankie, I usually am on some variant of a keto for weightlifting, but I&#039;m not a vegan, so I obtain most of my fat from heavy cream. As a vegan though, you could derive most of your fat from olive oil or coconut oil (if you can stomach it, it&#039;s hard, I&#039;ve tried). One benefit of using coconut oil for a keto is its a medium chain triglyceride (faster burning for energy than most fats) and actually produces ketones. You can find more info about coconut oil keto diets on Wikipedia if you poke around.</description>
		<content:encoded><![CDATA[<p>Hey Frankie, I usually am on some variant of a keto for weightlifting, but I&#8217;m not a vegan, so I obtain most of my fat from heavy cream. As a vegan though, you could derive most of your fat from olive oil or coconut oil (if you can stomach it, it&#8217;s hard, I&#8217;ve tried). One benefit of using coconut oil for a keto is its a medium chain triglyceride (faster burning for energy than most fats) and actually produces ketones. You can find more info about coconut oil keto diets on Wikipedia if you poke around.</p>
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		<title>By: frankie</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-67116</link>
		<dc:creator>frankie</dc:creator>
		<pubDate>Tue, 11 Dec 2012 04:18:00 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-67116</guid>
		<description>hi beth, I&#039;m vegan too, but how would I go about keto? not much  more to eat than than tofu or soy hot dogs. of course veggies but no seitan! can u please rec a site or a book? ty!</description>
		<content:encoded><![CDATA[<p>hi beth, I&#8217;m vegan too, but how would I go about keto? not much  more to eat than than tofu or soy hot dogs. of course veggies but no seitan! can u please rec a site or a book? ty!</p>
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		<title>By: DrKeto</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-67065</link>
		<dc:creator>DrKeto</dc:creator>
		<pubDate>Tue, 11 Dec 2012 02:30:26 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-67065</guid>
		<description>That&#039;s a fantastic way to lose lean body mass.</description>
		<content:encoded><![CDATA[<p>That&#8217;s a fantastic way to lose lean body mass.</p>
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		<title>By: melajara</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-67013</link>
		<dc:creator>melajara</dc:creator>
		<pubDate>Tue, 11 Dec 2012 00:17:57 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-67013</guid>
		<description>This is yet another reason to promote fasting (complete, i.e. no food, no soup, no tea, only pure water) for about a week or more if you endure it well. Do it at least two times per year.

But wait, why fasting is not more advised?

It was, it&#039;s a standard practice in all religions.

But nowadays, you don&#039;t hear it about it anymore, just because it&#039;s an anti-consumerist practice, it&#039;s SO BAD for the economy!

But it&#039;s GOOD for your body. Your choice, LOL</description>
		<content:encoded><![CDATA[<p>This is yet another reason to promote fasting (complete, i.e. no food, no soup, no tea, only pure water) for about a week or more if you endure it well. Do it at least two times per year.</p>
<p>But wait, why fasting is not more advised?</p>
<p>It was, it&#8217;s a standard practice in all religions.</p>
<p>But nowadays, you don&#8217;t hear it about it anymore, just because it&#8217;s an anti-consumerist practice, it&#8217;s SO BAD for the economy!</p>
<p>But it&#8217;s GOOD for your body. Your choice, LOL</p>
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		<title>By: Tom</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-66954</link>
		<dc:creator>Tom</dc:creator>
		<pubDate>Mon, 10 Dec 2012 22:07:34 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-66954</guid>
		<description>This type of diet is also non-inflammatory. It helped me conquer IBS and lost quite a bit of weight. Its nice to see the anti aging aspect of this as well. Awesome!</description>
		<content:encoded><![CDATA[<p>This type of diet is also non-inflammatory. It helped me conquer IBS and lost quite a bit of weight. Its nice to see the anti aging aspect of this as well. Awesome!</p>
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		<title>By: Beth</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-66916</link>
		<dc:creator>Beth</dc:creator>
		<pubDate>Mon, 10 Dec 2012 20:50:40 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-66916</guid>
		<description>“Over the years, studies have found that restricting calories slows aging and increases longevity — however the mechanism of this effect has remained elusive,” Dr. Verdin said. 

How about this mechanism: the less processing a machine does, the longer til it wears out? Is this so difficult?</description>
		<content:encoded><![CDATA[<p>“Over the years, studies have found that restricting calories slows aging and increases longevity — however the mechanism of this effect has remained elusive,” Dr. Verdin said. </p>
<p>How about this mechanism: the less processing a machine does, the longer til it wears out? Is this so difficult?</p>
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		<title>By: Beth</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-66913</link>
		<dc:creator>Beth</dc:creator>
		<pubDate>Mon, 10 Dec 2012 20:48:13 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-66913</guid>
		<description>Well, Mr. X, while millions are obese and dying from diabetes complications, we have federal health agencies promoting &quot;6-11&quot; servings of grain per day, and to get the majority of one&#039;s calories from carbohydrates (which, if not used immediately, are stored as fat).

The obsession with wheat in the West is for me at least as toxic as the obsession with refined (granulated) types of sugar, and the fried potatoes as a one&#039;s obligatory &quot;vegetable of the day&quot; doesn&#039;t help much. Add on top the recent trend toward fruit (because people&#039;s palates are too putrified with refined shite to even bear the thought of eating vegetables, health or no) and you can easily see why America is the fattest and sickest nation in the world.

And heart disease? Which is UNHEARD of outside nations who don&#039;t gorge themselves on animal products at every meal? Give me a break. These aren&#039;t mysterious rogue killers- they are directly due to institutionally-caused and deliberately-maintained ignorance on the part of the populace. The information is there, but no one looks further than industry propaganda. 

~ketogenic vegan~</description>
		<content:encoded><![CDATA[<p>Well, Mr. X, while millions are obese and dying from diabetes complications, we have federal health agencies promoting &#8220;6-11&#8243; servings of grain per day, and to get the majority of one&#8217;s calories from carbohydrates (which, if not used immediately, are stored as fat).</p>
<p>The obsession with wheat in the West is for me at least as toxic as the obsession with refined (granulated) types of sugar, and the fried potatoes as a one&#8217;s obligatory &#8220;vegetable of the day&#8221; doesn&#8217;t help much. Add on top the recent trend toward fruit (because people&#8217;s palates are too putrified with refined shite to even bear the thought of eating vegetables, health or no) and you can easily see why America is the fattest and sickest nation in the world.</p>
<p>And heart disease? Which is UNHEARD of outside nations who don&#8217;t gorge themselves on animal products at every meal? Give me a break. These aren&#8217;t mysterious rogue killers- they are directly due to institutionally-caused and deliberately-maintained ignorance on the part of the populace. The information is there, but no one looks further than industry propaganda. </p>
<p>~ketogenic vegan~</p>
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		<title>By: Mr.X</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-66900</link>
		<dc:creator>Mr.X</dc:creator>
		<pubDate>Mon, 10 Dec 2012 20:12:09 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-66900</guid>
		<description>Ha, take that high-carbies.And we, those adhering to any kind of low-carb &quot;doctrine&quot; (sometimes it seems people don&#039;t consult science on nutrition but preach gospel instead), look better as well;)

All these skinny-fat people giving advice on nutrition and sports, makes one- or at least me- think about the irrationality of our species.

Especially those state agencies giving the same old counsel that just doesn&#039;t work for the majority of people should consider an ideological move towards the side of science, as something that&#039;s actually done , instead of rehearsal based on old conclusions.

If it doesn&#039;t work, it&#039;s your fault, they say.This is rather cowardly.In the old days, the teacher (a role those giving advice take on by doing so) was responsible for the success of his (yes, mostly his;)) pupils.</description>
		<content:encoded><![CDATA[<p>Ha, take that high-carbies.And we, those adhering to any kind of low-carb &#8220;doctrine&#8221; (sometimes it seems people don&#8217;t consult science on nutrition but preach gospel instead), look better as well;)</p>
<p>All these skinny-fat people giving advice on nutrition and sports, makes one- or at least me- think about the irrationality of our species.</p>
<p>Especially those state agencies giving the same old counsel that just doesn&#8217;t work for the majority of people should consider an ideological move towards the side of science, as something that&#8217;s actually done , instead of rehearsal based on old conclusions.</p>
<p>If it doesn&#8217;t work, it&#8217;s your fault, they say.This is rather cowardly.In the old days, the teacher (a role those giving advice take on by doing so) was responsible for the success of his (yes, mostly his;)) pupils.</p>
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		<title>By: Cory</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-66876</link>
		<dc:creator>Cory</dc:creator>
		<pubDate>Mon, 10 Dec 2012 19:36:36 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-66876</guid>
		<description>Really? This is structurally similar to GHB which has been demonized by the media... follow the money to xyrem as to why. 

http://en.wikipedia.org/wiki/Gamma-Hydroxybutyric_acid</description>
		<content:encoded><![CDATA[<p>Really? This is structurally similar to GHB which has been demonized by the media&#8230; follow the money to xyrem as to why. </p>
<p><a href="http://en.wikipedia.org/wiki/Gamma-Hydroxybutyric_acid" rel="nofollow">http://en.wikipedia.org/wiki/Gamma-Hydroxybutyric_acid</a></p>
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		<title>By: Marnie</title>
		<link>http://www.kurzweilai.net/breakthrough-compound-generated-by-low-calorie-diet-blocks-effects-of-aging/comment-page-1#comment-66801</link>
		<dc:creator>Marnie</dc:creator>
		<pubDate>Mon, 10 Dec 2012 17:04:15 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=173935#comment-66801</guid>
		<description>This reminds me of several articles I&#039;ve read about fasting for a few days before chemo for cancer. The normal, healthy cells throttle down their metabolism, strengthen their cell membranes (perhaps with this chemical) and can greatly reduce side effects and in some cases, allow greater doses of the drug without harming normal cells so badly.</description>
		<content:encoded><![CDATA[<p>This reminds me of several articles I&#8217;ve read about fasting for a few days before chemo for cancer. The normal, healthy cells throttle down their metabolism, strengthen their cell membranes (perhaps with this chemical) and can greatly reduce side effects and in some cases, allow greater doses of the drug without harming normal cells so badly.</p>
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