Cell bio, automation merge to screen every human gene

April 1, 2010 | Source: Ars Technica

A paper published in this week’s Nature takes a method pioneered with C. elegans and extends it to the human genome: researchers have knocked down every single identified human gene, and used an automated imaging system to examine the impact on cell division.

All of the 190,000 movies that resulted have been made publicly accessible.

The surprise was that less than half of these genes had previously been implicated in cell division, so the work seems to be generating some significant new information.