Scientists from Forschungszentrum Julich have demonstrated that the 5-Hz Parkinson’s disease tremor results from synchronous signals from the thalamus and the basal ganglia transmitted in loop-like neuron pathways of the brain and spinal cord, not only via proprioceptive nerve signals from the muscles (the current theory).

The finding supports the use of a Jülich-developed deep brain pacemaker, which uses two electrodes to deliver mild, targeted, and desynchronized stimuli to interfere with synchronized neural signals.