Dartmouth Bioengineers Develop Humanized Yeast

September 2, 2003 | Source: KurzweilAI

Bioengineers at Dartmouth have genetically engineered yeast to produce humanized therapeutic proteins to address the manufacturing crunch currently confronting the biopharmaceutical industry.

Reported in this week’s issue of Science, the researchers have re-engineered the yeast P. pastoris to secrete a complex human glycoprotein — a process offering significant advantages over current production methods using mammalian cell lines, according to the researchers.

Dartmouth College press release