‘Electronic Switch’ Opens Doors In Rheumatoid Joints

January 3, 2008 | Source: Science Daily

University of Leeds scientists have identified a previously unknown natural mechanism that opens ion channels by donating electrons to them like “an electronic on-switch.”

The new mechanism occurs through the naturally occurring protein thioredoxin–a protein generated to counter inflammation–so the research could eventually lead to new treatments for inflammatory diseases such as rheumatoid arthritis.

Until now, two main groups of activating mechanisms have been acknowledged: changes in cell voltage and binding of chemical factors.