Comments on: Firefly gene makes mice glow to track cancer and aging in real time http://www.kurzweilai.net/firefly-gene-makes-mice-glow-to-track-cancer-and-aging-in-real-time Accelerating Intelligence Sat, 25 May 2013 17:00:03 +0000 hourly 1 http://wordpress.org/?v=3.4.1 By: Depressed optimist http://www.kurzweilai.net/firefly-gene-makes-mice-glow-to-track-cancer-and-aging-in-real-time/comment-page-1#comment-90412 Depressed optimist Tue, 22 Jan 2013 09:02:40 +0000 http://www.kurzweilai.net/?p=177232#comment-90412 What if immortal beings were first?. And over time developed limits to everything so socialiality would arise? Or else why would there be so many different "breakthroughs" and none if them really seem to correlate. My grandmother has dementia. The once intelligent brave and hilarious old gran she used to be is bricking herself up behind those damn protein blockades. I'd like to see her again. So make this work. Thanks lol What if immortal beings were first?. And over time developed limits to everything so socialiality would arise? Or else why would there be so many different “breakthroughs” and none if them really seem to correlate. My grandmother has dementia. The once intelligent brave and hilarious old gran she used to be is bricking herself up behind those damn protein blockades. I’d like to see her again. So make this work. Thanks lol

]]> By: Orwell Icecream http://www.kurzweilai.net/firefly-gene-makes-mice-glow-to-track-cancer-and-aging-in-real-time/comment-page-1#comment-90043 Orwell Icecream Mon, 21 Jan 2013 18:37:37 +0000 http://www.kurzweilai.net/?p=177232#comment-90043 We need more glow-in-the-dark pets! We need more glow-in-the-dark pets!

]]> By: nanotech.republika.pl http://www.kurzweilai.net/firefly-gene-makes-mice-glow-to-track-cancer-and-aging-in-real-time/comment-page-1#comment-89955 nanotech.republika.pl Mon, 21 Jan 2013 15:34:03 +0000 http://www.kurzweilai.net/?p=177232#comment-89955 Even for me, an ignorant person about all those bio research, this paper looks very exciting to me. If the progress of science and technology is marked by the progress in tool development, then this may rank very high. It is like a killer app I think. I wonder if you can use other genes linked to senescence or cancer, e.g. instead of p16 using p53. Or, beyond experimenting with toxins to make the cells cancerous or aged more quickly, maybe they should experiment with killing the senescent cells by using some drug. There was some paper before showing that only small fraction of cells in a body becomes senescent, so maybe you can experiment with this technology to kill them off. But on the other hand, looking at the pictures and diagrams in the paper, it looks like an old mouse is all lit up, so maybe it is not just a fraction of cells that gets the p16 turned on. Also, when I google for "p16 monitoring Luciferase" I get this (http://www.celldiv.com/content/5/1/1) paper from 2010, in which researchers were using the same technique. Is that right? Even for me, an ignorant person about all those bio research, this paper looks very exciting to me.

If the progress of science and technology is marked by the progress in tool development, then this may rank very high. It is like a killer app I think.

I wonder if you can use other genes linked to senescence or cancer, e.g. instead of p16 using p53. Or, beyond experimenting with toxins to make the cells cancerous or aged more quickly, maybe they should experiment with killing the senescent cells by using some drug. There was some paper before showing that only small fraction of cells in a body becomes senescent, so maybe you can experiment with this technology to kill them off. But on the other hand, looking at the pictures and diagrams in the paper, it looks like an old mouse is all lit up, so maybe it is not just a fraction of cells that gets the p16 turned on.

Also, when I google for “p16 monitoring Luciferase” I get this (http://www.celldiv.com/content/5/1/1) paper from 2010, in which researchers were using the same technique. Is that right?

]]> By: Editor http://www.kurzweilai.net/firefly-gene-makes-mice-glow-to-track-cancer-and-aging-in-real-time/comment-page-1#comment-89940 Editor Mon, 21 Jan 2013 14:54:38 +0000 http://www.kurzweilai.net/?p=177232#comment-89940 Thanks, fixed Thanks, fixed

]]> By: Starheart http://www.kurzweilai.net/firefly-gene-makes-mice-glow-to-track-cancer-and-aging-in-real-time/comment-page-1#comment-89919 Starheart Mon, 21 Jan 2013 13:38:08 +0000 http://www.kurzweilai.net/?p=177232#comment-89919 Uh, "Firefly", not "Firefire". Hopefully Joss Whedon won't get into genetic engineering... Uh, “Firefly”, not “Firefire”.

Hopefully Joss Whedon won’t get into genetic engineering…

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