http://www.kurzweilai.net/how-noise-in-brain-cell-signals-affects-neuron-response-time-and-thinking Accelerating Intelligence Sun, 19 May 2013 18:08:52 +0000 hourly 1 http://wordpress.org/?v=3.4.1 http://www.kurzweilai.net/how-noise-in-brain-cell-signals-affects-neuron-response-time-and-thinking/comment-page-1#comment-30933 graham caldwell Wed, 05 Sep 2012 15:30:17 +0000 http://www.kurzweilai.net/?p=159064#comment-30933 dear rob,thanks for your reply i will need to find out more about tinitus and then some. thanks again.graham. dear rob,thanks for your reply i will need to find out more about tinitus and then some. thanks again.graham.

]]> http://www.kurzweilai.net/how-noise-in-brain-cell-signals-affects-neuron-response-time-and-thinking/comment-page-1#comment-28535 Rob Hunter Fri, 17 Aug 2012 15:48:46 +0000 http://www.kurzweilai.net/?p=159064#comment-28535 One of the areas I do not see being utilized is the nervous system response during reasearch in neural function. The brain and the body are one. All living organisms have two purposes: Survive and mate. Using the example of danger, evolutionary imperative has determined that in times of extreme danger (extinction events) where the predator already has the "jump " on you that you not only need a neural decision response (do I fight,flight,freeze) but the body must be ready for that instant physical response. A plan that cannot be executed is no plan at all is it? In survival situations where miloseconds are the difference between life and extinction reacting pysically and cognitively is equally important which is why in times of danger our nervous system is alreading gearing up even before the signal (sensory input) has reached the brain. Thus when researching neural response you cannot get a clear pattern of neural function/firing unless you incorporate the nervous system as well. Simply, you're missing half of the picture which accounts for confusion and false-positives. Spike signal transmission influences can better be identified given two factors. 1- What was the cognitive neural function at the instant of new sensory input? 2- What is the "degree" of new sensory input? For example: I'm walking down the street with a friend talking and talking about the weather (prefrontal neural function) when I see something in a store window that catches my attention. Instant change in cognitive function/ spiking. We stop look and decide we're not interested which means neural function remains in the prefrontal cortex. 2- This time a man with gun suddenly appears. This new sensory input will instantly (through the amygala) send neural cognitive response into "extinction" mode. Extinction mode causes a shift from dominant neural function to shift from the prefrontal to the hippocampus as my brain begins to search for a response/survival tactic which has two equally important and simulataneous/synchronized responses these being cognitively and spatailly. What I mean to say is there is increased spiking and supression each time there is new sensory input. What is important is the degree of sensory input.That is another topic. What I am suggesting is that when attempting to identify spiking in neural function do not forget to look at the nervous system. There is a reason that the Hippocampus is divided into two areas. Memory and spatial. When not engaged in survival (or mating) the prefrontal rules. An easy test would be to engage a test subject in what I suggested (walking down the street) I garantee that by engaging "extinction" you will see massive spiking in not in just both spheres of the Hippocampus and nervous system but a marked supression in the prefrontal at the same instant. A simple way to test this theory might be by using the example of two friends walking doen the street. 1- Create a baseline of prefrontal spiking by having them discuss the weather. 2- Have them shift the conversation to sports which they are both passionate and opinionated about. Neural function at its core is emotional (we are what we experince) and there should be a marked shift in not only neural spiking and supression as the topic changes which also will show a marked increase in physical/nervous system baselines: blood pressure, heart rate etc as the argument over who will the upcoming game escalates. 3- When they spot something in a window that catches their interest (say a scantily clothed mannequinn thus keeping with Evolutionary Imperative of surviving long enough to procreate) you should see a dramatic shift from prefrontal neural function to the hippocampus and even more increased nervous system function that might include hastening their pace over to get a better look and changes in blood flow to different parts of the body. 4- Bring in the man with the gun and there should be a definative shift as the prefrontal becomes submissive and both spheres of the Hippocampus take complete control (you might also want to look for an extreme spike in the amygala) and search for a way to respond. That response, or the sucess of that response has everything do with previous experience/memory and is another topic for another day. I hope this helps. Rob Hunter One of the areas I do not see being utilized is the nervous system response during reasearch in neural function. The brain and the body are one. All living organisms have two purposes: Survive and mate. Using the example of danger, evolutionary imperative has determined that in times of extreme danger (extinction events) where the predator already has the “jump ” on you that you not only need a neural decision response (do I fight,flight,freeze) but the body must be ready for that instant physical response. A plan that cannot be executed is no plan at all is it? In survival situations where miloseconds are the difference between life and extinction reacting pysically and cognitively is equally important which is why in times of danger our nervous system is alreading gearing up even before the signal (sensory input) has reached the brain. Thus when researching neural response you cannot get a clear pattern of neural function/firing unless you incorporate the nervous system as well. Simply, you’re missing half of the picture which accounts for confusion and false-positives.
Spike signal transmission influences can better be identified given two factors.
1- What was the cognitive neural function at the instant of new sensory input?
2- What is the “degree” of new sensory input?
For example: I’m walking down the street with a friend talking and talking about the weather (prefrontal neural function) when I see something in a store window that catches my attention. Instant change in cognitive function/ spiking. We stop look and decide we’re not interested which means neural function remains in the prefrontal cortex.
2- This time a man with gun suddenly appears. This new sensory input will instantly (through the amygala) send neural cognitive response into “extinction” mode. Extinction mode causes a shift from dominant neural function to shift from the prefrontal to the hippocampus as my brain begins to search for a response/survival tactic which has two equally important and simulataneous/synchronized responses these being cognitively and spatailly.
What I mean to say is there is increased spiking and supression each time there is new sensory input. What is important is the degree of sensory input.That is another topic.
What I am suggesting is that when attempting to identify spiking in neural function do not forget to look at the nervous system. There is a reason that the Hippocampus is divided into two areas. Memory and spatial.
When not engaged in survival (or mating) the prefrontal rules. An easy test would be to engage a test subject in what I suggested (walking down the street) I garantee that by engaging “extinction” you will see massive spiking in not in just both spheres of the Hippocampus and nervous system but a marked supression in the prefrontal at the same instant.
A simple way to test this theory might be by using the example of two friends walking doen the street.
1- Create a baseline of prefrontal spiking by having them discuss the weather.
2- Have them shift the conversation to sports which they are both passionate and opinionated about. Neural function at its core is emotional (we are what we experince) and there should be a marked shift in not only neural spiking and supression as the topic changes which also will show a marked increase in physical/nervous system baselines: blood pressure, heart rate etc as the argument over who will the upcoming game escalates.
3- When they spot something in a window that catches their interest (say a scantily clothed mannequinn thus keeping with Evolutionary Imperative of surviving long enough to procreate) you should see a dramatic shift from prefrontal neural function to the hippocampus and even more increased nervous system function that might include hastening their pace over to get a better look and changes in blood flow to different parts of the body.
4- Bring in the man with the gun and there should be a definative shift as the prefrontal becomes submissive and both spheres of the Hippocampus take complete control (you might also want to look for an extreme spike in the amygala) and search for a way to respond. That response, or the sucess of that response has everything do with previous experience/memory and is another topic for another day.
I hope this helps.
Rob Hunter

]]> http://www.kurzweilai.net/how-noise-in-brain-cell-signals-affects-neuron-response-time-and-thinking/comment-page-1#comment-28430 graham caldwell Thu, 16 Aug 2012 13:53:10 +0000 http://www.kurzweilai.net/?p=159064#comment-28430 could the tuning process help deminish the noise of tinitus. could the tuning process help deminish the noise of tinitus.

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