Comments on: Making old muscles young again

By: Dr.Pratt

Dr.Pratt — Tue, 02 Oct 2012 15:15:21 +0000

I love how we evolved from the stem cell muscle problem to dog walking. Hmmmm. put the dog on a treadmill and yourself in the pool. (treadmill by the pool) Cant work with 3 dogs though.

By: Mr.X

Mr.X — Fri, 28 Sep 2012 16:52:48 +0000

@ Ralph: I know how you spotted me: “Incidentally — am I human or a bot? Remember, if you think I sound human, I am probably a bot, because only bots have the skills necessary to fake it.”

I need to readjust: Eat legs of dog, then they move won’t.Headsho!!1

By: Mr.X

Mr.X — Fri, 28 Sep 2012 16:11:02 +0000

Only one thing to you humans:
“Your cortex just doesn’t impress me,
so go ahead, try to turing test me.”

By: asiwel

asiwel — Fri, 28 Sep 2012 16:05:11 +0000

Well, I just read the article itself .. which, honestly was pretty opaque to me, but is still a fascinating and promising study! Mixed in with various inhibitors and other stuff, it appears that the “common drug” referred to above is Tamoxifen. Now this is NOT something I would probably recommend anybody to be taking to avoid muscle aging! This is one of those studies that we all need to “wait a few years” for useful results for people like us!

By: Christian Gehman

Christian Gehman — Fri, 28 Sep 2012 15:24:22 +0000

If you have 3 German Shepherds that won’t mind when they’re not on a leash, the problem is with your approach to dog training. Dogs will pull until you train them not to pull. You should be able to walk three German shepherds at your pace, not their pace. They;’ll behave when you train them. At present, it sounds like the dogs have trained you …. German shepherds are often overbred and can become frantic(from boredom) if not given enough to do. Working dogs that are not allowed to work develop odd mental habits. Just like people.

By: Christian Gehman

Christian Gehman — Fri, 28 Sep 2012 15:16:10 +0000

Get new knees.

By: Telekinetic

Telekinetic — Fri, 28 Sep 2012 15:11:44 +0000

You must take N-Acetyl Glucosamine because glucosamine is not as bioavailable. Vitamin K2 is important for calcium deposition on bones, as opposed to your arteries, which is also known as “hardening of the arteries”.
I also suggest MSM powder, a bioavailable form of sulfur, since many people report relief of joint pain. There are other natural supplements,that work for joint pain and arthritis. ” True CMO” (cetyl myristoleate) will also provide relief from arthritis.

By: tim the realist

tim the realist — Fri, 28 Sep 2012 14:22:09 +0000

hopefully this effect can be replicated in humans, maybe the inhibitor is already in widespread use and a study could be done to measure any muscular effects. I would expect reduced levels of heart attacks if the heart muscle regeneration capabilites were improved maybe this could put the walker and cane manufacturers out of business and we could all be physicaly fit into old age.

I’m also hopefull that there are competitive athletes trying to gain an edge using FGF2 inhibitors and acting as an uncontrolled stage 1 human trial :)

By: Editor

Editor — Fri, 28 Sep 2012 04:12:26 +0000

X marks the bot.

By: Ralph

Ralph — Fri, 28 Sep 2012 04:02:31 +0000

Mr. X is my kind of guy, I mean, bot.

By: nfordkrz

nfordkrz — Thu, 27 Sep 2012 22:42:20 +0000

In the retirement community in which I live, a lot of people ride in their golf carts while their dogs walk/run along side.

Re Glucosamine: I’ve taken it for over 10 years and still have bad joints. The reason I don’t stop taking them is that you never know if it might have been worse without them. And they don’t cost much.

By: Gorden Russell

Gorden Russell — Thu, 27 Sep 2012 21:12:31 +0000

I’ll write that down and look for it.

By: Gorden Russell

Gorden Russell — Thu, 27 Sep 2012 21:11:53 +0000

The last time I tried to run Franz alongside the bike he saw a squirrel off to the left and cut across my front wheel from the right and threw me over the handlebars.

By: Mr.X

Mr.X — Thu, 27 Sep 2012 18:55:37 +0000

Chinese solution: Just eat the dogs.

By: vspyder

vspyder — Thu, 27 Sep 2012 18:54:34 +0000

Can you take them for a walk beside you by riding a bike? This may not be possible if you take three at a time, but one at a time it would work.

By: Trinity Alps

Trinity Alps — Thu, 27 Sep 2012 18:18:01 +0000

So what was that common drug??? I’m getting older by the second! ;)

By: melajara

melajara — Thu, 27 Sep 2012 18:03:01 +0000

Or read the article about remotely controlled cockroaches
…
and connect the dots, LOL

By: Telekinetic

Telekinetic — Thu, 27 Sep 2012 16:51:48 +0000

Take N- Acetyl Glucosamine everyday plus other antioxidants like astaxanthin. I’m 57 and I can still outwalk your dogs.

By: Marcos Marin

Marcos Marin — Thu, 27 Sep 2012 16:46:20 +0000

Hire a dog-walker!

… but then you will have to worry who will pay his meals when robots can walk your dogs for him… hmmm I guess your knees will keep hurting till the singularity… or at least until solar cell powered nano bots can excrete carbon nano stuff from the air into your joints… tough luck.

By: gaoptimize

gaoptimize — Thu, 27 Sep 2012 16:02:24 +0000

OK. This raises an obvious question: Jack LaLanne and his kind. It seems to me his exercise was causing the repeated call-up of these muscle stem cells, and if there was a limited pool, his muscles would have wasted at a higher rate than a normal person. But the exact opposite was the case. I don’t buy that the pool of stem cells is limited. There is clearly much more study that needs to be done here, and it is about time given the exploding babyboomer population.

By: Gorden Russell

Gorden Russell — Thu, 27 Sep 2012 13:58:26 +0000

Let’s just hope these researchers get the funding to jump on this like a duck on a June bug. I’ve got three German shepherds who want a half-hour walk ever 90 minutes and my knees hurt.

By: melajara

melajara — Thu, 27 Sep 2012 12:07:18 +0000

“We do not yet know how or why levels of the protein FGF2 increase with age, triggering stem cells to be activated when they are not needed.,” said Kieran Jones, co-author of the study from King’s. ”This is something that needs to be explored.

Indeed, the path of causal relations has to be followed up and up till one primary cause is found.

Then, going down again, we’ll see that curing the primary defect should (hopefully) cure other ailments seemingly unrelated to what triggered the research, here muscle depletion.

But it could very well have unexpected bad effects too like e.g. cancer induction. Such is the complexity and beauty of biology.