This unique book addresses issues pertaining to nanomedical devices and systems design in terms of challenges, possibilities, and future vision. It examines what it takes to design, fabricate, and functionalize autonomous micron-scale, robotic medical devices (having nanometric-scale components) and what perceived hurdles must be overcome to foster their development and implementation. The book investigates device deployment and recovery strategies, as well as protocols for their safe and failsafe operation and their efficacy when applied to an array of human maladies.