Nanoparticles Replace Toxic Virus Vectors for Gene Therapy
December 31, 2004 | Source: KurzweilAI
A gene therapy method that doesn’t rely on potentially toxic viruses as vectors is being developed by University at Buffalo scientists.
The researchers delivered fluorescent genes to cells using nanoparticles as DNA carriers as an alternative vector to viruses. Using confocal microscopy and fluorescent spectroscopy, the scientists tracked transfection optically in real time, including the delivery of genes into cells, the uptake of genes by the nucleus and their expression.