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3D-bioprinting improved artificial blood vessels

The future: transplantable tissues customized to each patient's needs or be used outside the body to develop safe, effective drugs
June 11, 2014

Artificial blood vessels are created using hydrogel constructs that combine advances in 3-D bioprinting technology and biomaterials (credit: Khademhosseini Lab)

A Brigham and Women’s Hospital (BWH) team has created artificial blood vessels using a three-dimensional (3D) bioprinting technique.

The study is published online this month in Lab on a Chip.

“Engineers have made incredible strides in making complex artificial tissues such as those of the heart, liver and lungs,” said senior study author, Ali Khademhosseini, PhD, biomedical engineer, and director of the BWH Biomaterialsread more

3D-imaging brain tissue at 1 micron resolution

May 6, 2013

Image of the cerebral vascular system of a mouse obtained by 3D two-photon microscopy with addition of Lem-PHEA. (Credit: © B. van der Sanden and F. Appaix (Institut des Neurosciences de Grenoble))

A fluorescent dye that enables high-resolution (about 1 micron) 3D images of the cerebral vascular system has been synthesized by researchers at the Laboratoire de Chimie (CNRS) in France in collaboration with the Institut des Neurosciences (Université Joseph Fourier).

The “Lem-PHEA chromophore” dye fluoresces in the red-near infrared region biological transparency window using two-photon absorption and can pass through the skin. It features solubility in biological… read more

3D-printed ‘bionic’ ear melds electronics and biology

May 3, 2013

Scientists used 3-D printing to merge tissue and an antenna capable of receiving radio signals. Credit: Photo by Frank Wojciechowski

Scientists at Princeton University have used a 3D printer to create a functional ear that can “hear” radio frequencies up to microwave frequencies.

The researchers’ primary purpose was to explore an efficient and versatile means to merge electronics with tissue. The scientists used 3D printing of cells and nanoparticles, followed by cell culture to combine a small coil antenna with cartilage, creating what they term… read more

3D-printed circuit boards for solder-free printable electronics

May 7, 2012

solder_free_electronics

Given the schematic for a simple circuit, here’s how to make it a real circuit with the base components, some conductive thread, and a 3D printer — no solder, no etching chemicals, no sending away for anything, Instructables explains in a how-to tutorial.

“We are entering an age where physical goods increasingly have a digital representation (e.g., www.thingiverse.com) — and the means of production of such goods are… read more

3D-printed cyborg muscle produces artificial heartbeat

February 26, 2013

artificial heartbeat

You might expect a robot’s heartbeat to be a metallic ticking. But the pulsing in this video isn’t completely artificial: it’s powered by living material, New Scientist reports.

Created by Peter Walters from the University of the West of England in Bristol, UK, and colleagues, the pump uses the gas released by live yeast to generate pressure and distend a membrane, turning it into an… read more

3D-printed ears that look and act like the real thing

February 22, 2013

ear

Cornell bioengineers and Weill Cornell Medical College physicians have created an artificial ear that looks and acts like a natural ear, giving new hope to thousands of children born with a congenital deformity called microtia.

They used 3-D printing and injectable gels made of living cells to fashion ears that are practically identical to a human ear.

Over a three-month period, these flexible ears… read more

3D-printed microscopic cages confine bacteria in tiny zoos for the study of infections

October 10, 2013

The researchers use a novel 3-D printing technology to build homes for bacteria at a microscopic level. The resulting structures (imaged in red through confocal fluorescence) can be of almost any shape or size, and can be moved around in relationship to other structures containing bacterial microcommunities (imaged in green).<br />
Credit: Courtesy of Jason Shear

By caging bacteria in microscopic houses, scientists at The University of Texas at Austin are studying how communities of bacteria, such as those found in the human gut and lungs, interact and develop infections.

In a recent experiment, they demonstrated that a community of Staphylococcus aureus, which can cause some skin infections, became more resistant to antibiotics when it was contained within a larger community of Pseudomonasread more

3D-printed rocket parts

November 11, 2012

NASA_M2_Cusing_Machine

NASA’s Marshall Space Flight Center is using ”selective laser melting” (SLM) to create intricate metal parts for America’s Space Launch System (SLS) heavy-lift rocket, saving millions in manufacturing costs.

SLM is similar to 3-D printing (additive printing) and is the future of manufacturing, says Ken Cooper, advanced manufacturing team lead at the Marshall Center.

“This machine takes metal powder and uses a high-energy laser to… read more

3D-printed tumor model allows for more realistic testing of how cancer cells grow and spread

April 15, 2014

3D cellular morphology on day 8

A group of researchers in China and the U.S. has created a 3D-printed model of a cancerous tumor to help discover new anti-cancer drugs and better understand how tumors develop, grow, and spread throughout the body.

The model consists of a scaffold of fibrous proteins (gelatin, alginate, and fibrin) corresponding to the extracellular matrix (support structure) of a tumor, in the form of a grid structure 10… read more

3D-printed-anatomy developers aim to revolutionize medical education

July 22, 2014

Part of the ‘3D Printed Anatomy Series’ thought to be the first commercially available resource of its kind (credit: Monash University)

A kit of 3D-printed anatomical body parts could revolutionize medical education and training, according to its developers at Monash University.

Professor Paul McMenamin, Director of the University’s Centre for Human Anatomy Education, said the simple and cost-effective anatomical kit would dramatically improve trainee doctors’ and other health professionals’ knowledge and could even contribute to the development of new surgical treatments.

“Many medical… read more

3D-printing food in space

June 3, 2013

ISSfood

NASA and a Texas company are exploring the possibility of printing food on a 3D printer on deep space missions.

NASA has awarded a Small Business Innovation Research (SBIR) Phase I contract to Systems and Materials Research Consultancy of Austin, Texas to conduct a study for the development of a 3D printed food system for long duration space missions.

As NASA ventures farther into space, whether… read more

3D-printing human embryonic stem cells for drug testing, future replacement of human organs

New 3D printing process is first to print the more delicate (and more useful) hESCs
February 6, 2013

3D printing with embryonic stem cells (credit: )

A new 3D printing process using human stem cells could pave the way to custom replacement organs for patients, eliminating the need for organ donation and immune suppression, and solving the problem of transplant rejection.

The process, developed at Edinburgh-based Heriot-Watt University, in partnership with Roslin Cellab, could also speed up and improve the process of reliable, animal-free drug testing by growing three-dimensional human tissues and structures… read more

3D-printing miniaturized medical implants, compact electronics, tiny robots, and more

June 24, 2013

For the first time, a research team from the Wyss Institute at Harvard University and the University of Illinois at Urbana-Champaign demonstrated the ability to 3D-print a battery. This image shows the interlaced stack of electrodes that were printed layer by layer to create the working anode and cathode of a microbattery. [Ke Sun, Teng-Sing Wei, Jennifer Lewis, Shen J. Dillon]

A team based at Harvard University and the University of Illinois at Urbana-Champaign has printed precisely interlaced stacks of tiny battery electrodes, each less than the width of a human hair

3D printing can now be used to print lithium-ion microbatteries the size of a grain of sand. The printed microbatteries could supply electricity to tiny devices in fields from medicine to communications, including many that have… read more

3D-printing multi-material objects in minutes instead of hours

November 22, 2013

A computer model of a pair of tweezers shows the distribution of materials and degrees of hardness in the object to be 3-D printed in Dr. Yong Chen's lab at USC Viterbi.</p>
<p>Credit: USC Viterbi

In another leap for 3D printing, researchers at the USC Viterbi School of Engineering have developed a faster 3D printing process that allows for 3D-printing multi-material objects in minutes instead of hours.

Fabrication time and the complexity of multi-material objects have been a hurdle to widespread use of 3D printing.

Speeding up printing

USC Viterbi researchers developed improved mask-image-projection-based stereolithography (MIP-SL) to drastically… read more

3D-printing non-toxic biocompatible medical implants

October 25, 2013

scaffold_for_tissue_engineering

A common vitamin — riboflavin (vitamin B2) — has made it possible to 3D-print non-toxic medical implants, researchers from North Carolina State University, the University of North Carolina at Chapel Hill and Laser Zentrum Hannover have discovered.

“This opens the door to a much wider range of biocompatible implant materials, which can be used to develop customized implant designs using 3-D printing technology,” says Dr.… read more

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