March 27, 2014
Reversing the conventional process of creating new drugs, Vanderbilt University researchers have used an alternative approach called bioretrosynthesis to produce the expensive HIV drug didanosine.
“These days synthetic chemists can make almost any molecule imaginable in an academic laboratory setting,” said Vanderbilt associate professor of chemistry Brian Bachmann, who first proposed bioretrosynthesis four years ago. “But they can’t always make them cheaply or in large quantities. Using… read more