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A molecular map for aging in mice

November 29, 2007

Researchers at the National Institute of Aging and Stanford University have used gene arrays to identify genes whose activity changes with age in 16 different mouse tissues.

The study describes how aging affects different tissues in mice, and ultimately could help explain why lifespan is limited to just two years in mice.

A Molecular Map of Aging

December 4, 2007

Researchers at Stanford University and the National Institute on Aging have generated a database that catalogues how gene expression–a measure of how active a gene is–changes in different parts of the body as the animals age.

The findings suggest that different tissues age very differently, and this could help pinpoint when it is appropriate to use mice as a model of human aging–and when it’s not.

A molecular ‘switch’ to reprogram control pathways in cells

"Molecular network diverter" can tweak the control systems that regulate the inner workings of cells, leading to future medical interventions to switch off diseased states or turn on healthy processes
August 20, 2013

molecular diverter2

Stanford University bioengineer has helped develop a technology dubbed a “molecular network diverter” that can tweak the control systems that regulate the inner workings of cells, pointing the way toward future medical interventions that could switch off diseased states or turn on healthy processes.

This molecular diverter uses the concerted action of three biological sub-systems to redirect signaling pathways — complex networks of molecular interactions that… read more

A ‘molecule scanner’ — world’s smallest teraHertz detector

August 7, 2013

Experimental setup to demonstrate the feasibility of generating THz field at nanoscale. A nanojunction, consisting of a ∼10 nm wide nanowire with a<br />
∼10 nm insulating barrier, is fabricated a<br />
interface with c-AFM lithography. Ultrafast (∼30 fs) optical pulses from a Ti:Sapphire laser are divided into “pump” and “probe” beams by a Mach−Zehnder interferometer.

Molecules could soon be “scanned” in a fashion similar to imaging screenings at airports, thanks to a detector developed by University of Pittsburgh physicists.

The detector may have the ability to chemically identify single molecules using terahertz radiation — a range of light far lower in frequency (0.1 to 30 THz) than visible light but higher than microwaves.

Terahertz radiation is commonly used in airport scanners.… read more

A Moment Of Tooth

January 6, 2009

The tooth will probably be the first complex organ to be completely regenerated from stem cell, University of Southern California researchers say.

Groups in Japan and Taiwan and at the University of Michigan are using stem cells to create hard and soft tissue in humans. The idea is to take a tooth about to fall out and reconnect it firmly.

A more powerful ‘lab-on-a-chip’ for genetic analysis

August 2, 2011

Microfluidic chip (credit: University of British Columbia)

Researchers at the University of British Columbia (UBC) have invented a microfluidic silicone chip that could make genetic analysis more sensitive, rapid, and cost-effective by allowing individual cells to fall into place like balls in a pinball machine.

The UBC device — about the size of a nine-volt battery — allows scientists to simultaneously analyze 300 cells individually by routing fluid-carrying cells through microscopic tubes… read more

A More Robust Grid for Manhattan

May 28, 2007

Supercooled, superconducting power cables are being examined as a way to add redundancy in the cramped quarters of Manhattan’s local power grid, potentially protecting against natural disruptions and terrorist attacks.

A More Sensitive Cancer Breathalyzer

August 31, 2009

Sensors that can detect volatile organic compounds present in the breath of lung-cancer patients (and for certain other ailments, such as liver failure), using an array of small, inexpensive gold nanoparticles, have been developed by Israel Institute of Technology researchers.

Clinical trials are expected within two or three years.

A more sensitive sensor using nano-sized carbon tubes

March 23, 2010

Miniature sensors that are able to sense the movement of individual atoms — 100 times more sensitive than any sensor device on the market today — are being developed by Tel Aviv University researchers.

The device uses carbon nanotubes that arrange themselves on a surface of a silicon chip. Small deformities in the crystal structure of the nanotubes generate a piezoelectric voltage that can be used to accurately sense… read more

A mouse that can regenerate its tissues

February 5, 2004

Researchers at the European Molecular Biology Laboratory and the University of Rome have found a way to mobilize stem cells to achieve a major regeneration of damaged tissue.

The scientists investigated muscle tissue in mice, discovering that stem cells can travel large distances to reach an injury. They also found a special form of a protein called mIGF-1 induces the muscle to send the distress signal that summons them.… read more

A moveable, flexible display made of paper

September 12, 2013

flexpad

Flexpad transforms a standard sheet of paper into a moveable, flexible display.

The technology was developed in the “Flexpad” research project under the leadership of Jürgen Steimle in the MIT Media Lab and the Max Planck Institute for Informatics in Saarbrücken, in cooperation with Kiel University.

“We routinely deform objects intuitively in many different ways. We bend back pages in books, deflate… read more

A multi-photon approach to quantum cryptography

Information breach may be drastically reduced as a result of a technology breakthrough
October 5, 2012

kak_three_stage_protocol

University of Oklahoma researchers have,  demonstrated a novel technique for cryptography that offers the potential of unconditional security.

As increasing volumes of data become accessible, transferable and, therefore actionable, information is the treasure companies want to amass.

To protect this wealth, organizations use cryptography, or coded messages, to secure information from “technology robbers.” This group of hackers and malware creators increasingly is becoming more sophisticated at… read more

A multifunctional nano carrier to detect, diagnose, and deliver drugs to cancer cells

October 31, 2013

uc_nano_carrier

A unique nanostructure developed by a team of international researchers* promises improved all-in-one detection, diagnoses, and drug-delivery treatment of cancer cells.

It can carry a variety of cancer-fighting materials on its double-sided (Janus) surface and within its porous interior and can:

  •  Transport cancer-specific detection nanoparticles and biomarkers to a site within the body, e.g., the breast or the prostate. This promises earlier diagnosis than is

read more

A Musical Score for Disease

July 18, 2008

Gil Alterovitz, a research fellow at Harvard Medical School, is developing a computer program that translates protein and gene expression into music.

In his acoustic translation, harmony represents good health, and discord indicates disease.

Using data collected from a study of protein expression in colon cancer, Alterovitz analyzed more than three thousand related proteins involved in the disease. He found four key networks, using various genetic databases that… read more

A Mysterious Link Between Sleeplessness and Heart Disease

December 26, 2008

People who don’t get much sleep are more likely than those who do to develop calcium deposits in their coronary arteries, possibly raising their risk for heart disease, a new study has found.

The researchers concluded that one hour more of sleep per night was associated with a 33 percent decrease in the odds of calcification.

Possible mechanims include higher levels of the stress hormone cortisol with less… read more

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