August 7, 2014
Researchers at Yale School of Medicine have discovered a new drug compound that reverses the brain deficits of Alzheimer’s disease in mice. Their findings are published in the Aug. 5 issue of the journal PLoS Biology (open access).
The compound, TC-2153, inhibits the negative effects of a protein called STtriatal-Enriched tyrosine Phosphatase (STEP) on learning and memory. These cognitive functions are impaired in Alzheimer’s.
“Decreasing STEP levels reversed… read more