science + technology news

This vitamin stops the aging process in organs, say Swiss researchers

A potential breakthrough for regenerative medicine, pending further studies
May 6, 2016

Improved muscle stem cell numbers and muscle function in NR-treated aged mice.<br />
Newly regenerated muscle fibers 7  days  after  muscle  damage  in  aged  mice (left: control group; right: fed NR) (Scale bar = 50 μm). (credit: Hongbo Zhang et al./Science)

EPFL researchers have restored the ability of mice organs to regenerate and extend life by simply administering nicotinamide riboside (NR) to them.

NR has been shown in previous studies to be effective in boosting metabolism and treating a number of degenerative diseases. Now, an article by PhD student Hongbo Zhang published in Science also describes the restorative effects of NR on the functioning of stem cells… read more

A robot for ‘soft tissue’ surgery outperforms surgeons

Let's say you're having intestinal surgery. Which do you choose: human or robot surgeon?
May 4, 2016

The STAR robot suturing intestinal tissue (credit: Azad Shademan et al./Science Translational Medicine)

Can a robot handle the slippery stuff of soft tissues that can move and change shape in complex ways as stitching goes on, normally requiring a surgeon’s skill to respond to these changes to keep suturing as tightly and evenly as possible?

A Johns Hopkins University and Children’s National Health System research team decided to find out by using their  “Smart Tissue Autonomous Robot” (STAR)… read more

Ultrasound allows for transmitting HD video through animal tissues

Imagine a miniature remote-controlled HD video camera that streams live video from a patient's intestines to a physician
April 27, 2016

Beef liver and pork loin were used to represent the density and moisture content found in human tissue (credit: UIUC)

University of Illinois at Urbana-Champaign engineers have demonstrated real-time video-rate (>30Mbps) “meat comm” data transmission through tissue, which could mean in-body ultrasonic communications may be possible for implanted medical devices, including hi-def video.

For example, a patient could swallow a miniaturized HD video camera that could stream live to an external screen, with the orientation of the device controlled wirelessly and externally by a physician, according to Andrewread more

Just 1 minute of intense exercise produces health benefits similar to 50 minutes of moderate exercise

No time to exercise? Now you have no excuse.
April 27, 2016

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Researchers at McMaster University have found that a single minute of very intense exercise within a 10-minute session produces health benefits similar to those from 50 minutes of moderate-intensity continuous exercise.

Brief bursts of intense exercise are remarkably effective, a very time-efficient workout strategy, according to Martin Gibala, a professor of kinesiology at McMaster and lead author on the study, published online in an open-access paper in the… read more

Machine learning rivals human skills in cancer detection

April 22, 2016

Samsung Medison RS80A ultrasound system (credit: Samsung)

Two announcements yesterday (April 21) suggest that deep learning algorithms rival human skills in detecting cancer from ultrasound images and in identifying cancer in pathology reports.

Samsung Medison, a global medical equipment company and an affiliate of Samsung Electronics, has just updated its RS80A ultrasound imaging system with a deep learning algorithm for breast-lesion analysis.

The “S-Detect for Breast” feature uses big data collected… read more

Scientists shoot anticancer drugs deep into tumors

Ultrasonic vibrations cause gas microbubbles to explode, releasing nanoparticles containing anticancer drugs
April 18, 2016

Schematic of magnetic microbubbles used in the study contain gas cores (blue) and shells of magnetic iron-oxide nanoparticles (red), forming a dense shell (center) around a drug-containing nanoparticles. When stimulated by ultrasound at resonant frequencies, the nanoparticles can travel hundreds of micrometers into tumor tissue.  (credit:  Yu Gao et al./NPG Asia Materials)

Scientists at Nanyang Technological University (NTU Singapore) have invented a new way to deliver cancer drugs deep into tumor cells.

They created micro-sized gas bubbles coated with anticancer drug particles embedded in iron oxide nanoparticles and used MRI or other magnetic sources to direct these microbubbles to gather around a specific tumor. Then they used ultrasound to vibrate the microbubbles, providing the energy to direct the drug particles into… read more

Ultrathin organic material enhances e-skin displays

More than next-gen medical displays: they're also ultra mood rings and a new art form
April 15, 2016

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University of Tokyo researchers have developed technology to enable creation of electronic skin (e-skin) displays of blood oxygen level, e-skin heart rate sensors for medical, athletic uses, and other applications.

To serve as a demo, they’ve created an ultrathin, ultraflexible, protective layer and created an air-stable, organic light-emitting diode (OLED) display.

For use in electronic devices integrated into the human body, wearable electronics need to… read more

Creating custom drugs on a portable refrigerator-size device

A breakthrough for responding quickly to disease outbreak and producing small quantities of custom drugs needed for clinical trials, treating rare diseases, or use as personalized "orphan drugs"
April 1, 2016

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MIT researchers have developed a compact, portable pharmaceutical manufacturing system that can be reconfigured to produce a variety of drugs on demand — if you have the right chemicals.

The device could be rapidly deployed to produce drugs needed to handle an unexpected disease outbreak, to prevent a drug shortage caused by a manufacturing plant shutdown, or produce small quantities of drugs needed for clinical trials or… read more

Nanoparticle ‘cluster bombs’ destroy cancer cells

New delivery method directly penetrates tumor cells, avoiding toxic side effects of cisplatin chemotherapy drug
March 30, 2016

nanoparticle cluster bomb_ft

Scientists have devised a triple-stage stealth “cluster bomb” system for delivering the anti-cancer chemotherapy drug cisplatin, using nanoparticles designed to break up when they reach a tumor:

  1. The nanoparticles start out relatively large  — 100 nanometers wide — so that they can move through the bloodstream and smoothly transport into the tumor through leaky blood vessels.
  2. As they detect acidic conditions close to tumors, the nanoparticles discharge

read more

New type of molecular tag makes MRI 10,000 times more sensitive

Could detect biochemical processes in opaque tissue without requiring PET radiation or CT x-rays
March 25, 2016

Duke scientists have discovered a new class of inexpensive and long-lived molecular tags that enhance MRI signals by 10,000-fold. To activate the tags, the researchers mix them with a newly developed catalyst (center) and a special form of hydrogen (gray), converting them into long-lived magnetic resonance “lightbulbs” that might be used to track disease metabolism in real time. Credit: Thomas Theis, Duke University

Duke University researchers have discovered a new form of MRI that’s 10,000 times more sensitive and could record actual biochemical reactions, such as those involved in cancer and heart disease, and in real time.

Let’s review how MRI (magnetic resonance imaging) works: MRI takes advantage of a property called spin, which makes the nuclei in hydrogen atoms act like tiny magnets. By generating a strong… read more

A wearable graphene-based biomedical device to monitor and treat diabetes

March 22, 2016

GP-hybrid-Electrochemical-Device-Array-on-the-Human-Skin-ft

A  wearable graphene-based patch that allows for accurate non-invasive blood-sugar diabetes monitoring and painless drug delivery has been developed by researchers at The Institute for Basic Science (IBS) Center for Nanoparticle Research in South Korea.

The device uses a hybrid of gold-doped graphene and a serpentine-shape gold mesh to measure pH (blood acidity level) and temperature by measuring the amount of glucose in sweat. If abnormally high levels… read more

Major steps toward a bioengineered heart for transplantation

Using a patient’s own cells may overcome problems associated with receiving a heart donated by another person
March 17, 2016

A partially recellularized human whole-heart cardiac scaffold, reseeded with human cardiomyocytes derived from induced pluripotent stem cells, being cultured in a bioreactor that delivers a nutrient solution and replicates some of the environmental conditions around a living heart. (credit: Bernhard Jank, MD, Ott Lab, Center for Regenerative Medicine, Massachusetts General Hospital)

Massachusetts General Hospital (MGH) researchers have taken early steps towards producing a bioengineered heart for transplantation that would use cells from the patient receiving the heart.

Using a patient’s own cells would help to overcome some of the problems associated with receiving a heart donated by another person, including immune rejection of the donated heart, as well as the long-term side effects of life-long treatment with the immunosuppressive… read more

New synthesized molecule could reduce brain damage in stroke victims

March 14, 2016

This graphic depicts a new inhibitor, 6S, locking up an enzyme (red) to block the production of hydrogen sulfide (yellow and white). Hydrogen sulfide concentrations have been shown to climb after the onset of a stroke, leaving to brain damage. (credit: Matthew Beio, University of Nebraska-Lincoln)

A new molecule known as 6S has reduced the death of brain tissue from ischemic stroke by up to 66 percent in rats while reducing the accompaning inflammation, researchers at the University of Nebraska-Lincoln and the National University of Singapore reported March 9 in an open-access paper published by the journal ACS Central Science.

The inhibitor molecule works by binding to cystathionine beta-synthase… read more

Are you ready for soft, morphing, crawling robots with glowing skin displays?

Turn and face the strange.
March 11, 2016

Morphing_displays_ft

Your future robot or mobile device could have soft, morphable, stretchable “skin” that displays information, according to research by Cornell University engineers. Imagine a health-care robot that displays your blood glucose level and oxygenation, and even your mood — perhaps also your remote physician’s face in 3D.

“When robots become more and more a part of our lives, the ability for them to have an emotional connection with… read more

Amputee feels texture with a ‘bionic’ fingertip

Other artificial-touch uses include robotics in surgery, rescue, and manufacturing
March 10, 2016

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Amputee Dennis Aabo Sørensen is the first person in the world to recognize texture (smoothness vs. roughness) using an artificial “bionic” fingertip surgically connected to nerves in his upper arm. The experimental system was developed by EPFL (Ecole polytechnique fédérale de Lausanne) and SSSA (Scuola Superiore Sant’Anna).

“The stimulation felt almost like what I would feel with my hand,” says Sørensen. “I felt the texture sensations at the tip of… read more

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