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Single stem cell capable of regenerating the entire blood system found

July 8, 2011

Scientists at the McEwen Centre for Regenerative Medicine and the Ontario Cancer Institute have isolated a human blood stem cell in its purest form: as a single stem cell capable of regenerating the entire blood system.

“This discovery means we now have an increasingly detailed road map of the human blood development system, including the much sought after stem cell,” says principal investigator… read more

Single virus gene may cause obesity

April 7, 2008

Louisiana State University researchers have shown that a single viral gene from adenovirus-36 can cause obesity by triggering fat precursor cells to differentiate into fat cells.

30 per cent of obese people and 11 per cent of people of average weight already have antibodies against the virus, suggesting prior infection by adenovirus-36.

Single-atom transistor created

December 7, 2009

(a) Scanning electron microscope image of single-atom transistor (b) Differential conductance through the transistor with 4 Tesla magnetic field

A working transistor whose active region comprises only of a single phosphorus atom in silicon has been built by researchers from Helsinki University of Technology, University of New South Wales, and University of Melbourne.

The device uses sequential tunneling of single electrons between the phosphorus atom and the source and drain leads of the transistor. The tunneling can be suppressed or allowed by controlling the voltage on a nearby… read more

Single-atom transistor is ‘end of Moore’s Law’ and ‘beginning of quantum computing’

February 20, 2012

A controllable transistor engineered from a single phosphorus atom has been developed by researchers at the University of New South Wales, Purdue University and the University of Melbourne. The atom, shown here in the center of an image from a computer model, sits in a channel in a silicon crystal. The atomic-sized transistor and wires might allow researchers to control gated qubits of information in future quantum computers. (Credit: Purdue University)

The smallest transistor ever built has been created using a single phosphorous atom by an international team of researchers at the University of New South Wales, Purdue University and the University of Melbourne.

The latest Intel chip, the “Sandy Bridge,” uses a manufacturing process to place 2.3 billion transistors 32 nanometers apart.

A single phosphorus atom, by comparison, is just 0.1 nanometers across, which would significantly reduce… read more

Single-cell RNA sequencing yields genetic makeup of human and mouse embryos in unprecedented detail

Are we about to usher in a new age of eugenics and designer babies?
August 2, 2013


UCLA scientists, in collaboration with teams in China, have used the powerful technology of single-cell RNA sequencing to track the genetic development of a human and a mouse embryo at an unprecedented level of accuracy.

The technique could lead to earlier and more accurate diagnoses of genetic diseases — even when the embryo consists of only eight cells.

The study was led by Guoping… read more

Single-chip device to provide real-time ultrasonic 3D images from inside the heart and blood vessels

February 24, 2014

A single-chip catheter-based device that would provide forward-looking, real-time, three-dimensional imaging from inside the heart, coronary arteries and peripheral blood vessels is shown being tested (credit: Georgia Tech Photo, Rob Felt)

The technology for a device that would provide real-time 3D imaging from inside the heart, coronary arteries, and peripheral blood vessels has been developed by Georgia Institute of Technology researchers.

With its volumetric imaging, the new device could better guide surgeons working in the heart and allow more of patients’ clogged arteries to be cleared without major surgery.

The device integrates ultrasound transducers with processing electronics… read more

Single-electron transistor allows for nanoscale ‘Etch A Sketch’ designs of ultra-dense memories

April 19, 2011

Single Electron

A University of Pittsburgh-led team has created a 1.5 nanometer single-electron transistor that provides a building block for ultra-dense computer memories, advanced electronic materials, and the basic components of quantum computers.

The SketchSET (sketch-based single-electron transistor) is the first single-electron transistor made entirely of oxide-based materials, and consists of an island formation that can house up to two electrons. The number of electrons on the central island… read more

Single-molecule electronic DNA sequencing

September 24, 2012


A team of researchers at Columbia University, have developed a novel approach to potentially sequence DNA in nanopores electronically at the single molecule level with single-base resolution.

This work, entitled “PEG-Labeled Nucleotides and Nanopore Detection for Single Molecule DNA Sequencing by Synthesis,” is now available in the open access online journal, Scientific Reports.


The major roadblock in DNA sequencing has been the cost and speed of obtaining… read more

Single-molecule electronic switch supports six logic states

December 5, 2011

Single-molecule switch (credit: University of Pittsburgh/Nano Letters)

Another single-molecule electronic switch has been invented by researchers at the University of Pittsburgh, with the advantage of integration into multiple-logic-state molecular devices, according to the researchers.

The switch could also enable smaller, faster and more energy-efficient electronics.

How it works

The prototype switch was created by embedding a triangular cluster of Sc3N (scandium nitride) — three metal atoms held together by a nitrogen atom… read more

Single-Molecule Magnets Open New Door for Information Technology

March 17, 2009
Fe4 molecule on gold surface (A. Cornia and M. Mannini)

Recent research by scientists in Italy and France shows that that single molecules have the ability to store information via their magnetic state –a first step toward a new generation of ultra-compact data storage technologies based on individual molecules.

Single-molecule motor sits on a single-atom ball bearing

Can be run forward or in reverse, depending on where electrons are injected
December 31, 2012

The base of the device holds a Ru atom, and the five-armed device can rotate on top of it (credit:

Researchers have created a reversible rotor that sits atop a ball bearing — a single ruthenium atom, Ars Technica reports.

The base of the system involves a boron atom that coordinates three ringed structures that are chemically similar to the bases of DNA. Nitrogens at a corner of these ringed structures coordinate the ruthenium atom, placing it at the peak of a three-sided pyramid.

The ruthenium atom acts… read more

Single-molecule switch opens the door to biomolecular electronics

February 22, 2005

Scientists from the Biodesign Institute at Arizona State University have created the first reproducible single molecule negative differential resistor and in the process have developed a groundbreaking experimental technique that provides a “roadmap” for designing single-molecule devices based on biochemistry.

Arizona State University news release

Single-photon transmitter could enable new quantum devices

Long-sought ability to transmit single photons while blocking multiple photons is finally achieved
July 26, 2012


A team of researchers at MIT and Harvard University has achieved a crucial long-sought goal for quantum devices: the ability to convert a laser beam into a stream of single photons in a controlled way.

In theory, quantum computers should be able to perform certain kinds of complex calculations much faster than conventional computers, and quantum-based communication could be invulnerable to eavesdropping.

But producing quantum components… read more

Single-pixel camera could simplify imaging

October 6, 2006

A single-pixel camera that captures complete images by taking many snaps with an array of micro-mirrors could consume less power and produce more compact image files than conventional imaging devices.

The camera switches each mirror randomly between one of two positions — so that they either reflect light onto the pixel or do not. The current version repeats this process about a thousand times in a second, recording the… read more

Single-pixel camera takes on digital

January 18, 2007

Rice University researchers are developing a single-pixel camera to capture high-quality images without the expense of traditional digital photography.

This “digital micromirror device” consists of a million or more tiny mirrors each the size of a bacterium. The light is focused through a second lens on to one single photodetector. As the light passes through the device, the millions of tiny mirrors are turned on and off at random… read more

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