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Test tube method analyzes and reconstitutes DNA-repair mechanism

December 15, 2004

One of five known DNA-repair mechanisms in cells has been completely analyzed and reconstituted in a test tube by an international collaboration of researchers led by scientists from the Keck School of Medicine.

The team is the first to reconstitute this pathway, known as the nonhomologous end joining pathway, or NHEJ, and NHEJ is only the third repair pathway to be reconstituted in the laboratory.

The ability to… read more


February 14, 2005

After more than a decade of development, Avida’s digital organisms at Michigan State University are now getting close to fulfilling the definition of biological life.

These are digital organisms — strings of commands — akin to computer viruses. Each organism can produce tens of thousands of copies of itself within a matter of minutes. Unlike computer viruses, however, they are made up of digital bits that can mutate and… read more

Testing Drugs with Stem Cells

December 13, 2007

University of Wisconsin-Madison researchers have developed a novel way to test drug toxicity by monitoring the behavior of embryonic stem cells exposed to a drug-candidate compound.

Testing the toxicity of pharmaceutical candidates in lab rats before the compounds are judged safe enough for human clinical trials is notoriously unreliable. Often compounds that appear safe in the rodents prove to be toxic in humans.

Studying how potential drugs affect… read more

Testing for bacteria in minutes instead of weeks

July 2, 2013


EPFL researchers have built a matchbox-sized device that can test for the presence of bacteria in a couple of minutes, instead of up to several weeks.

A nano-lever vibrates in the presence of bacterial activity, while a laser reads the vibration and translates it into an electrical signal that can be easily read: absence of a signal signifies the absence of bacteria.

This makes… read more

Testing Over, to Open Its TV and Film Offerings This Week

March 11, 2008 will make its catalog of TV shows and video clips available to anyone on the Web starting Wednesday.

The streaming-video site displays free, ad-supported shows and feature films from NBC, Fox and more than 50 media companies, including Sony Pictures and Metro-Goldwyn-Mayer.

Testing the Toxicity of Nanomaterials

June 6, 2008

Massachusetts General Hospital researchers and colleagues have developed a high-throughput screening method to test the toxicity of nanomaterials.

A robotic system (similar to that used for drug screening) puts nanoparticles inside tiny wells on a plate containing hundreds of separate wells. Each well contains one cell type. The system detects changes in the cells’ metabolism in response to the nanomaterial.

Testing: A User’s Guide

May 1, 2007

Doctors are developing new tests and guidelines for asthma, bone and cartilage defects, colon cancer, heart disease, obesity, and diabetes.

Tests Begin on Drugs That May Slow Aging

August 20, 2009

Excitement among researchers on aging has picked up in the last few years with the apparent convergence of two lines of inquiry: single gene changes and the caloric-restriction diet.

Tests that show machines closing in on human abilities

January 22, 2009

New ways are being developed to test how well machines can match aspects of human intelligence, including animated human faces, androids, a jazz improvization program, and military robots.

Tethered molecules act as light-driven reversible nanoswitches

June 24, 2008
(Paul Weiss lab, Penn State)

Penn State University and Rice University scientists have developed a new technique for attaching light-sensitive organic molecules to metal surfaces that allows the molecules to be switched between two different configurations in response to exposure to different wavelengths of light.

This research advance is the first step in designing a device that can be driven or actuated by such molecular change. It could perform useful work as… read more

Texas Approves a $4.93 Billion Wind-Power Project

July 20, 2008

Texas regulators have approved a $4.93 billion wind-power transmission project, providing a major lift to the development of wind energy in the state.

Texas wind farms increase land surface temperature

May 2, 2012

Wind Farm

A Texas region containing four of the world’s largest wind farms showed an increase in land surface temperature over nine years that researchers have connected to local meteorological effects of the turbines.

The land surface temperature around the west-central Texas wind farms warmed at a rate of .72 degrees Celsius per decade during the study period relative to nearby regions without wind farms, an effect most likely… read more

Text Compressor 1% Away From AI Threshold

July 10, 2007

Alexander Ratushnyak compressed the first 100,000,000 bytes of Wikipedia to a record-small 16,481,655 bytes, thereby winning the second payout of The Hutter Prize for Compression of Human Knowledge and bringing text compression within 1 percent of the threshold for artificial intelligence estimated by the founder of information theory, Claude Shannon.

Text mining: what do publishers have against this high-tech research tool?

May 25, 2012


Researchers are pushing to make tens of thousands of papers based on publicly funded research work available through open access to find links between genes and diseases — countering publishers’ default ban on text mining via computer scanning.

That would allow researchers to mine the content freely without needing to request any extra permissions.

Researchers often need access to tens of thousands of research papers at once, so they can use computers… read more

Text-to-Speech Technology Reaches an Inflection Point

September 18, 2009

People with speech-impairing conditions like A.L.S., autism, Down syndrome and strokes have started to discover that general-purpose devices, such as iPhones and netbooks equipped with downloadable text-to-speech software, can in many cases help them communicate better and more cheaply than the expensive proprietary speech devices covered by Medicare and private health insurance.

In addition, disease experts say that children with Down syndrome often prefer to have a standard computer… read more

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