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Bioteeth generated from your own cells

March 12, 2013

Current design of a dental implant (credit: American Association of Oral and Maxillofacial Surgeons)

Researchers are developing a method to replace missing teeth with new bioengineered teeth generated from a person’s own gum cells.

Current implant-based methods of whole tooth replacement fail to reproduce a natural root structure and as a consequence of the friction from eating and other jaw movement, loss of jaw bone can occur around the implant.

Research towards producing bioengineered teeth (bioteeth) has largely focused on generating… read more

Biotech’s Sparse Harvest

February 14, 2006

The next generation of biotech crops — the first with direct benefits for consumers — is finally on the horizon. But the list does not include many of the products once envisioned.

Developing such crops has proved to be far from easy. Resistance to genetically modified foods, technical difficulties, legal and business obstacles, and the ability to develop improved foods without genetic engineering have winnowed the pipeline.

Biotech’s Bright Hopes

May 23, 2001

About 350 drugs are in late-stage clinical trials, but there are expensive hurdles to federal approval.

Cures for pulmonary hypertension, diabetic neuropathy, and some forms of cancer are among the possibilities.

Biotech Takes on New Industries

March 11, 2005

Biotech is making inroads in chemical, fuel, oil, plastics, detergents, textiles, and other industrial areas.

Biotech is thrusting us into new political territory

August 29, 2012

Human_fetus_10_weeks_with_amniotic_sac

Stem cells, embryo research and synthetic biology are just a few of the issues that will force strange new political alliances, University of Pennsylvania bioethicist Jonathan D. Moreno writes in New Scientist.

The new biology, or biotechnology — including stem cells, embryo research, synthetic biology and reproductive technology — has unprecedented power to change basic life processes.

One recent example is the controversy over the “three-parent… read more

Biotech firms target artificial blood

February 11, 2002

Scientists may be close to an elusive goal of creating artificial blood, a breakthrough that could ease shortages and save countless lives.

Biopure Corp. in Cambridge, Mass., has produced artificial hemoglobin from the red blood cells of cows. It has been cleared for use in the Republic of South Africa and is awaiting Food and Drug Administration review of its phase III clinical trials in the United States. U.S.… read more

Biotech data mining

January 2, 2006

In the last ten years, biotech companies have been busy accumulating mountains of data. And it’s becoming more and more difficult to find useful information about interactions between genes and proteins for example.

It’s one of the reasons why the European Union has started the BioGrid project. The researchers involved in it have delivered a better search engine for PubMed by analyzing over-expressing genes and predicting the protein interactions… read more

Biotech Company to Auction Chances to Clone a Dog

May 23, 2008

BioArts International will auction off five opportunities to have a dog cloned, with the bidding to start at $100,000.

The company has produced one set of verified dog clones internally. Dogs are among the most difficult animals to clone because they have an unusual reproductive biology, more so than humans. The first cloned dog was born in 2005.

Biotech a healthy market for chips

August 15, 2003

Intel is planning to develop medical devices using nanotech chips and sensing technology.

Ideas include constructing hemoglobin molecules that can carry 10 times as much oxygen, a diagnostic lab on a chip, toxin-detecting and analysis-capable bandaids, ulcer-detecting stockings for diabetics, and computer feedback systems for diagnosis and treatment of Alzheimer’s Disease.

Biosensors on the fast track

March 17, 2011

Nerve stimulator (photo credit: FDA)

The Food & Drug Administration has teamed up with the Defense Advanced Research Projects Agency (DARPA) to help accelerate the development and approval of innovative devices for continuously monitoring biomarkers in people.

Biomarkers can serve as early warning signs of disease — such as diabetes, cardiovascular disease, and influenza — before symptoms occur, ideally in real time. They could also help optimize the performance of… read more

Biosensors comfortable enough to wear 24-7

July 6, 2010

wireless_brain_x220

Replacing sticky EEG (brain wave) electrodes, UCSD researchers have built a capacitive EEG sensor, which conducts much weaker signals but can do so across small distances.

The sensor can detect faint changes in capacitance, and amplify them, while canceling out the ambient electrical noise that exists all around us. When multiple sensors are embedded in material and wired together, they create a portable monitor that patients can… read more

Biosensor patch monitors brain, heart, muscle signals

April 22, 2013

A close-up view of the Bio-patch (credit: KTH The Royal Institute of Technology)

The future of health care could be found in a tiny, paper-thin skin patch that collects vital information.

The Bio-patch sensor developed by KTH Royal Institute of Technology researchers is inexpensive, versatile, and comfortable to wear. It measures bioelectrical signals through the skin when applied to different parts of the body.

“On the chest it provides electrocardiography (ECG), on the skull it measures brainwaves… read more

Bioscientists: Gods or Monsters?

May 30, 2005

In his new book, The Geneticist Who Played Hoops With My DNA … and Other Masterminds From the Frontiers of Biotech, journalist and author David Ewing Duncan chats with some of the most prominent and powerful life scientists in the United States about the human motivations behind their God-like endeavors.

Bioprinted 3D liver-mimicking device detoxifies blood

May 16, 2014

ucsd-bioprinted-liver

Nanoengineers at the University of California, San Diego have developed a 3D-printed device inspired by the liver to remove dangerous toxins from the blood.

The device, which is designed to be used outside the body — much like dialysis — uses nanoparticles to trap pore-forming toxins that can damage cellular membranes and are a key factor in illnesses that result from animal bites and stings, and bacterial… read more

Biophysicists unravel cellular ‘traffic jams’ in active transport

December 5, 2012

This image depicts motor protein traffic along a single microtubule highway. Much like vehicular traffic in real life, kinesin motor traffic reduces the velocity of single motors. Multi-motor “cargos,” such as the quantum dot depicted, can stay attached to the microtubule much longer because they can add multiple motors. (Credit: Leslie Conway and Jennifer Ross/UMass Amherst)

UMass Amherst biophysicists, using a unique microscope, have improved upon earlier studies that used too-simple models not able to account for the densely crowded, dynamic conditions of a active transport in a real cell

Inside many growing cells, an active transport system runs on nano-sized microtubule tracks that resemble a highway, complete with motors carrying cargo quickly from a central supply depot to growing tips or wherever… read more

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