science + technology news

Stem Cell Ruling Will Be Appealed

August 25, 2010

The Obama administration said Tuesday that it would appeal a court ruling challenging the legality of President Obama’s rules governing human embryonic stem cell research.

The head of the National Institutes of Health said the decision would most likely force the cancellation of dozens of experiments in diseases ranging from diabetes to Parkinson’s, and suspend $54 million in financing for 22 scientific projects by the end of September. An additional 60 projects are threatened.

Stem cell superpowers exposed

June 16, 2006

Biologists say they are close to finding a cellular elixir of youth: a cocktail of proteins that can convert adult cells into embryonic stem cells that are able to grow replacement tissues, according to two studies published in Nature June 14.

If found, this recipe could leapfrog the intense controversy involved in extracting stem cells from a human embryo, which is destroyed in the process.

Instead, doctors might… read more

Stem cell surprise for tissue regeneration

June 26, 2009

Genes that make muscle stem cells in the embryo are surprisingly not needed in adult muscle stem cells to regenerate muscles after injury, scientists working at the Carnegie Institution’s Department of Embryology with colleagues have found.

The finding challenges the current course of research into muscular dystrophy, muscle injury, and regenerative medicine, which uses stem cells for healing tissues, and favors using age-matched stem cells for therapy.

Stem Cell Test Tried on Mice Saves Embryo

October 17, 2005

Scientists have devised two new techniques to derive embryonic stem cells in mice, one of which avoids the destruction of the embryo, a development that could have the potential to shift the grounds of the longstanding political debate about human stem cell research.

The second new technique manipulates embryos so they are inherently incapable of implanting in the uterus, a possible ethical advantage in the proposed therapy.

Both… read more

Stem cell therapy safety boosted

March 10, 2005

A new way of growing human embryonic stem cells in the laboratory will reduce the risk that their use in therapy could go wrong, say scientists.

At present the cells are cultured using live animal cells, which carries the risk of contamination with viruses and other harmful agents. Researchers at Advanced Cell Technology in Boston have developed a method that replaces the use of animal cells with a sterile… read more

Stem cell therapy trials to mend shattered bones

February 19, 2008

University of Edinburgh researchers have developed new methods to use a patient’s own stem cells to repair damaged bones and cartilage, using a “bioactive scaffold” to protect the stem cells and stimulate their growth into bone or cartilage.

The method could treat conditions such as osteoarthritis and trauma victims whose bones have been shattered beyond repair.

University of Edinburgh News Release

Stem cell transplant ‘cures’ diabetic mice (Preview)

February 11, 2008

The prospect of using transplants derived from human embryonic stem cells (hESCs) to reverse Type I diabetes has come a step closer with the news that the technique seems to work in mice, according to scientists from San Diego based Novocell.

The Novocell team grew hESCs in the lab until they differentiated into insulin-producing islet cells. The cells were injected into the abdomens or backs of mice whose own… read more

Stem cell versatility could help tissue regeneration

August 19, 2010

stemcellvers

European scientists have reprogrammed stem cells from the thymus to grow skin and hair cells, in a development that could have implications for tissue regeneration. Their research shows that it is possible to convert one stem type to another without the need for genetic modification.

The researchers, who used rat models, grew stem cells from the thymus in the laboratory using conditions for growing hair follicle skin stem cells.… read more

Stem Cells Are Where It’s At

December 6, 2006

There are now more than 1,000 stem-cell therapies in early human trials around the world.

Last month saw the first patient treated with embryonic cells, which have triggered much debate in the United States. After years of being thought of as science fiction, stem-cell therapies are becoming a scientific fact.

Stem cells can become ‘normal sperm’

May 8, 2003

New research suggests it might be possible to take an individual’s cell, create embyronic stem cells from it by therapeutic cloning, and then derive healthy eggs or sperm from them for use in IVF.

The most obvious application would be to treat infertile women who cannot produce any eggs suitable for IVF, or men who cannot produce sperm. And because male ESCs can be turned into eggs as well… read more

Stem Cells Changed Into Precursors For Sperm, Eggs

October 29, 2009

Stanford University School of Medicine. researchers have devised a way to efficiently coax human embryonic stem cells to become human germ cells — the precursors of egg and sperm cells — in the laboratory.

Unlike previous research, which yielded primarily immature germ cells, the cells in this study functioned well enough to generate sperm cells.

Stem cells contain immortal DNA

July 3, 2006

Scientists at the Pasteur Institute have shown for the first time the mechanism that adult muscle stem cells use to protect their DNA from mutations: they retain the original DNA strands.

Understanding this has important implications for cancer research, the study of gene regulation, and ultimately growing stem cells of therapeutic potential in the laboratory.

Stem cells ‘could restore vision’

October 27, 2004

University of Toronto scientists found that human retinal stem cells regenerated when they were transplanted into the eyes of mice and chicks.

These stem cells could eventually be used to restore normal vision in people with sight problems, the researchers say.

Stem cells develop into kidney cells

July 25, 2001

Adult stem cells taken from bone marrow can develop into kidney cells, British scientists have discovered.
Bone marrow stem cells, which are immature blood cells, have already been shown to transform into liver, nerve and muscle cells.

Both adult and embryonic stem cells have enormous medical potential due to their ability to mature into a wide range of different tissues, which could then be transplanted. However, ethical considerations have… read more

Stem cells found in adults may repair nerves

February 18, 2004

Researchers have learned that some nerves, even nerves in parts of the brain, can regenerate or be replaced, using stem cells. However, the pace of stem-cell repairs in humans is slow. And in some cases, they can even impede healing.

“We’re studying ways that this process is regulated to see if it can be manipulated to promote healing,” according to Dr. Philip Horner, an assistant professor in the Department… read more

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