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Imaging the 3D structure of a single virus

Using the intense beam of the world’s most powerful x-ray free-electron laser (XFEL)
March 2, 2015

Three-dimensional reconstruction of the giant mimivirus particle with an X-ray<br />
free-electron laser (credit: Tomas Ekeberg et al./Physical Review Letters)

By measuring a series of diffraction pattern from a virus injected into an XFEL beam, researchers at Stanford’s Linac Coherent Light Source (LCLS) have determined the first three-dimensional structure of a virus, using a mimivirus.

X-ray crystallography has solved the vast majority of the structures of proteins and other biomolecules. The success of the method relies on growing large crystals of the molecules, which isn’t possible for all molecules.… read more

We can make multicore chips smarter, faster — we have the technology

March 2, 2015

(credit: Christine Daniloff/MIT)

Computer chips’ clocks have stopped getting faster, so chipmakers are instead giving chips more cores, which can execute computations in parallel.

Now, in simulations involving a 64-core chip, MIT computer scientists have improved a system that cleverly distributes data around multicore chips’ memory banks — increasing system computational speeds by 46 percent while reducing power consumption by 36 percent.

“Now that the way to improve performance is to add… read more

Researchers ‘overclocking’ world’s fastest supercomputers to process big data faster

"Approximate computing" tricks use controlled errors to achieve speed increases and reduce power consumption
March 2, 2015

High performance computing (HPC) systems (credit: Queens University Belfast)

Researchers at Queen’s University Belfast, the University of Manchester, and the STFC Daresbury Laboratory are developing new software to increase the ability of supercomputers to process big data faster while minimizing increases in power consumption.

To do that, computer scientists in the The Scalable, Energy-Efficient, Resilient and Transparent Software Adaptation (SERT) project are using “approximate computing” (also known as “significance-based computing”) — a form of “overclocking” that trades reliability… read more

Schmidhuber to do AMA (Ask Me Anything) on reddit /r/MachineLearning

March 1, 2015


Jürgen Schmidhuber, Director of the Swiss Artificial Intelligence Lab (IDSIA), will do an AMA (Ask Me Anything) on reddit/r/MachineLearning on Wednesday March 4, 2015 at 10 AM EST. You can post questions now in advance in this thread.

A key figure in AI in Europe and noted for his quirky sense of humor, Schmidhuber’s ideas and writing have been featuredread more

Quantum radar could detect stealth cancer cells or aircraft

February 27, 2015

quantum radar ft.

A prototype “quantum radar” that has the potential to detect objects that are invisible to conventional systems has been developed by an international research team led by a quantum information scientist at the University of York.

The new breed of radar is a hybrid system that uses quantum correlation between microwave and optical beams to detect objects of low reflectivity such as cancer cells or aircraft with a stealth… read more

A superconductor advance using ‘superatoms’

February 27, 2015

Superconductivity is the ability to transmit electricity without resistance (credit: USC/Original image/DC Comics Mystery in Space #56, December 1959)

USC scientists may have discovered a family of superconductor materials called superatoms that could lead to room-temperature supercomputers.

A team led by Vitaly Kresin, professor of physics at the USC Dornsife College of Letters, Arts and Sciences, found that aluminum “superatoms” — homogenous clusters of atoms — appear to form Cooper pairs of electrons (one of the key elements of superconductivity) at temperatures around 100 Kelvin.

Though 100… read more

Puzzling bright spots on dwarf planet Ceres

February 27, 2015

(credit: NASA / JPL-Caltech / UCLA / MPS / DLR / IDA)

Cruising through the asteroid belt, NASA Dawn spacecraft is approaching dwarf planet Ceres, and some puzzling features are coming into focus, revealing craters and mysterious bright spots.

“We expected to be surprised by Ceres,” says Chris Russell, principal investigator of the Dawn mission, based at UCLA. “We did not expect to be this puzzled. … As Dawn has come closer to Ceres, the bright spots have become brighter and… read more

Controlling pain by optogenetic stimulation of the brain’s pain center

February 27, 2015

Pain-reduction experimental setup: (upper) optical fiber mounted via cannula in mouse brain; (lower) saline or Formalin injection in hind paw (credit: Ling Gu et al./PLoS ONE)

A small area of the brain called the anterior cingulate cortex (ACC) in the thalamus can be optically stimulated to control pain, University of Texas at Arlington scientists have found.

The researchers used optogenetic stimulation with a blue laser to control pain sensation in a mouse, created by a chemical irritant (formalin) and mechanical pain, such as that experienced following a pinprick or pinch.

“Our results… read more

A ‘breakthrough’ in rechargeable batteries for electronic devices and electric vehicles

February 26, 2015


Researchers from Singapore’s Institute of Bioengineering and Nanotechnology (IBN) of A*STAR and Quebec’s IREQ (Hydro-Québec’s research institute) have synthesized a new material that they say could more than double the energy capacity of lithium-ion batteries, allowing for longer-lasting rechargeable batteries for electric vehicles and mobile devices.

The new material for battery cathodes (the + battery pole) in based on a “lithium orthosilicate-related” compound,  Li2MnSiO4, combining lithium, manganese, silicon and oxygen,… read more

Deep astronomy: automated 3D observations of the universe

February 26, 2015

The MUSE instrument on ESO’s Very Large Telescope reveals previously invisible galaxies (credit: ESO)

The MUSE instrument on ESO’s Very Large Telescope (VLT) in Chile recently gave astronomers the best-ever 3D view of the deep Universe.

After staring at the Hubble Deep Field South (HDF-S) region for just 27 hours, the new observations and automated analysis revealed details, distances, motions, spectra, compositions, and other properties of 189 galaxies, more than ten times the number of measurements of distance in this tiny piece of… read more

Graphene shown to neutralize cancer stem cells

February 26, 2015

Graphene oxide targeting cancer stem cells with differentiation-based nano-therapy (credit: Marco Fiorillo et al./Oncotarget)

University of Manchester scientists have used graphene oxide to target and neutralize cancer stem cells (CSCs) while not harming other cells.

This new development opens up the possibility of preventing or treating a broad range of cancers, using a non-toxic material.

In combination with existing treatments, this finding could eventually lead to tumor shrinkage as well as preventing the spread of cancer and its… read more

Cancer risk linked to DNA ‘wormholes’

February 25, 2015

dna spiral

Single-letter genetic variations within parts of the genome once dismissed as “junk DNA” can increase cancer risk through remote effects on far-off genes, new research by scientists at The Institute of Cancer Research, London shows.

The researchers found that DNA sequences within “gene deserts” — so called because they are completely devoid of genes — can regulate gene activity elsewhere by forming DNA loops across… read more

Magnetic nanoparticles could stop blood-clot-caused strokes and heart attacks

Could destroy blood clots 1000 times faster than a commonly used clot-busting technique
February 25, 2015

Schematic representation of clot-busting tissue plasminogen activator (tPA) drug (green) hidden in serum albumin camouflage (gray), surrounding a core of 20 nm magnetic iron-oxide nanoparticles (red) (credit: Eszter Voros et al./Advanced Functional Materials)

Houston Methodist researchers have developed magnetic nanoparticles that in tests delivered drugs to destroy blood clots up to 1000 times faster than a commonly used clot-busting technique.

If the drug delivery system performs similarly well in planned human clinical trials, it could mean a major step forward in the prevention of strokes, heart attacks, pulmonary embolisms, and other dire circumstances where clots — if not quickly busted… read more

European roadmap for graphene science and technology published

February 24, 2015

AFM lithography-graphene

In an open-access paper published today in the Royal Society of Chemistry journal Nanoscale, more than 60 academics and industrialists lay out a science and technology roadmap for graphene, related two-dimensional crystals, other 2d materials, and hybrid systems based on a combination of different 2d crystals and other nanomaterials.

The roadmap covers the next 10 years and beyond, intended to guide the research community and… read more

Brain makes decisions with same method used to break WW2 Enigma code

February 24, 2015

An Enigma machine at the Walker Library of the History of Human Imagination (credit: Michael Shadlen)

When making simple decisions, neurons in the brain apply the same statistical trick used by Alan Turing to help break Germany’s Enigma code during World War II, according to a new study in animals by researchers at Columbia University’s Mortimer B. Zuckerman Mind Brain Behavior Institute and Department of Neuroscience.

Results of the study were published Feb. 5 in Neuron.

As depicted in… read more

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