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	<title>Comments on: Promising compound restores memory loss and reverses symptoms of Alzheimer&#8217;s</title>
	<atom:link href="http://www.kurzweilai.net/promising-compound-restores-memory-loss-and-reverses-symptoms-of-alzheimers/feed" rel="self" type="application/rss+xml" />
	<link>http://www.kurzweilai.net/promising-compound-restores-memory-loss-and-reverses-symptoms-of-alzheimers</link>
	<description>Accelerating Intelligence</description>
	<lastBuildDate>Sat, 25 May 2013 19:00:28 +0000</lastBuildDate>
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		<title>By: Dr. X</title>
		<link>http://www.kurzweilai.net/promising-compound-restores-memory-loss-and-reverses-symptoms-of-alzheimers/comment-page-1#comment-84381</link>
		<dc:creator>Dr. X</dc:creator>
		<pubDate>Sun, 06 Jan 2013 10:19:16 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=175952#comment-84381</guid>
		<description>Yeah it is patented already and stay that way for next 20 years..</description>
		<content:encoded><![CDATA[<p>Yeah it is patented already and stay that way for next 20 years..</p>
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		<title>By: Gabriel</title>
		<link>http://www.kurzweilai.net/promising-compound-restores-memory-loss-and-reverses-symptoms-of-alzheimers/comment-page-1#comment-84138</link>
		<dc:creator>Gabriel</dc:creator>
		<pubDate>Sat, 05 Jan 2013 04:13:08 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=175952#comment-84138</guid>
		<description>What a wonderful article; I&#039;m happy to read any progress in alleviating this horrible condition.</description>
		<content:encoded><![CDATA[<p>What a wonderful article; I&#8217;m happy to read any progress in alleviating this horrible condition.</p>
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		<title>By: JC</title>
		<link>http://www.kurzweilai.net/promising-compound-restores-memory-loss-and-reverses-symptoms-of-alzheimers/comment-page-1#comment-84025</link>
		<dc:creator>JC</dc:creator>
		<pubDate>Fri, 04 Jan 2013 19:14:17 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=175952#comment-84025</guid>
		<description>Biohackers unite!  Make the TFP5 tonight!  Safety first, but fear no patent right!</description>
		<content:encoded><![CDATA[<p>Biohackers unite!  Make the TFP5 tonight!  Safety first, but fear no patent right!</p>
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		<title>By: Bruce Wright</title>
		<link>http://www.kurzweilai.net/promising-compound-restores-memory-loss-and-reverses-symptoms-of-alzheimers/comment-page-1#comment-84019</link>
		<dc:creator>Bruce Wright</dc:creator>
		<pubDate>Fri, 04 Jan 2013 18:51:15 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=175952#comment-84019</guid>
		<description>Yes, there are many treatments that work very well in mice but don&#039;t work nearly as well (or at all) in humans.  But there are also a lot of similarities, so something like this (even if not this identical molecule) is very likely work in humans as well.  One obvious potential problem is whether this disease process in mice is really similar on a molecular level with that in humans;  another is that all too often by the time Alzheimer&#039;s has been diagnosed there is already a great deal of damage and tissue loss.  Still, even if we can&#039;t restore the person&#039;s full intellectual capacity, if it can just halt the disease process and restore a significant part of their brain function, that can make the difference between being able to do basic daily activities or not, and would be a huge improvement in quality of life to those who already have fairly advanced Alzheimer&#039;s.  Additionally, it would make it even more important to be able to diagnose the disease early, before there was too much damage and while the treatment might be able to prevent most or all of the intellectual decline associated with the disease.

Clearly a major advance in our understanding of the disease process of this horrible disease.</description>
		<content:encoded><![CDATA[<p>Yes, there are many treatments that work very well in mice but don&#8217;t work nearly as well (or at all) in humans.  But there are also a lot of similarities, so something like this (even if not this identical molecule) is very likely work in humans as well.  One obvious potential problem is whether this disease process in mice is really similar on a molecular level with that in humans;  another is that all too often by the time Alzheimer&#8217;s has been diagnosed there is already a great deal of damage and tissue loss.  Still, even if we can&#8217;t restore the person&#8217;s full intellectual capacity, if it can just halt the disease process and restore a significant part of their brain function, that can make the difference between being able to do basic daily activities or not, and would be a huge improvement in quality of life to those who already have fairly advanced Alzheimer&#8217;s.  Additionally, it would make it even more important to be able to diagnose the disease early, before there was too much damage and while the treatment might be able to prevent most or all of the intellectual decline associated with the disease.</p>
<p>Clearly a major advance in our understanding of the disease process of this horrible disease.</p>
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		<title>By: GatorALLin</title>
		<link>http://www.kurzweilai.net/promising-compound-restores-memory-loss-and-reverses-symptoms-of-alzheimers/comment-page-1#comment-83973</link>
		<dc:creator>GatorALLin</dc:creator>
		<pubDate>Fri, 04 Jan 2013 15:53:08 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=175952#comment-83973</guid>
		<description>...sorry if that came off sarcastic.... just that there are some slight differences from humans to mice...  Of course my fingers are crossed that this same tool works just as well in humans (or better), but my gut says nothing is quite that simple. Lets hope this research opens the door for human trials faster.</description>
		<content:encoded><![CDATA[<p>&#8230;sorry if that came off sarcastic&#8230;. just that there are some slight differences from humans to mice&#8230;  Of course my fingers are crossed that this same tool works just as well in humans (or better), but my gut says nothing is quite that simple. Lets hope this research opens the door for human trials faster.</p>
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		<title>By: GatorALLin</title>
		<link>http://www.kurzweilai.net/promising-compound-restores-memory-loss-and-reverses-symptoms-of-alzheimers/comment-page-1#comment-83972</link>
		<dc:creator>GatorALLin</dc:creator>
		<pubDate>Fri, 04 Jan 2013 15:50:13 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=175952#comment-83972</guid>
		<description>..now if you will just take this pill Mr. Smith, it will switch your human brain for that of a mouse brain and then we can save you.....</description>
		<content:encoded><![CDATA[<p>..now if you will just take this pill Mr. Smith, it will switch your human brain for that of a mouse brain and then we can save you&#8230;..</p>
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		<title>By: Gorden Russell</title>
		<link>http://www.kurzweilai.net/promising-compound-restores-memory-loss-and-reverses-symptoms-of-alzheimers/comment-page-1#comment-83939</link>
		<dc:creator>Gorden Russell</dc:creator>
		<pubDate>Fri, 04 Jan 2013 14:20:17 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=175952#comment-83939</guid>
		<description>Right, tim, this TFP5 just might spare us from Alzheimer’s so that we can live on to see the Singularity.</description>
		<content:encoded><![CDATA[<p>Right, tim, this TFP5 just might spare us from Alzheimer’s so that we can live on to see the Singularity.</p>
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		<title>By: tim the realist</title>
		<link>http://www.kurzweilai.net/promising-compound-restores-memory-loss-and-reverses-symptoms-of-alzheimers/comment-page-1#comment-83922</link>
		<dc:creator>tim the realist</dc:creator>
		<pubDate>Fri, 04 Jan 2013 12:59:47 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=175952#comment-83922</guid>
		<description>Hopefully this drug will also work in humans to alleviate the symptoms until a cure can be found for this horrible disease.</description>
		<content:encoded><![CDATA[<p>Hopefully this drug will also work in humans to alleviate the symptoms until a cure can be found for this horrible disease.</p>
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