Researchers at Karolinska Institutet have discovered that signalling via a receptor molecule called nogo receptor 1 (NgR1) in the nerve membrane plays a key part in forming lasting memories during the first week after an event.

The scientists hope that their findings will eventually help in the development of new treatments for memory impairments, such as those related to Alzheimer’s and stroke. Medicines designed to target the NgR1 receptor system should be able to improve the brain’s ability to form long-term memories.