‘Switched on’ muscle stem cells morph to resemble nerve cells

April 15, 2004 | Source: KurzweilAI

Researchers have turned muscle progenitor cells — stem cells that are “committed” to becoming muscle tissue — into cells that look and act like neurons.

Using an artificial gene they created, the researchers “switched on” a panel of genes that are normally silent in the muscle cells, causing them to morph into cells that show biochemical, physiological, and structural properties of neurons.

The researchers say the advance provides evidence that stem cells could be profoundly “flexible” — able to develop into different cell types.

University of Texas M. D. Anderson Cancer Center news release