Synthetic windpipe is used to replace cancerous one

January 13, 2012 | Source: New York Times
windpipe

A trachea made from plastic, above, and seeded with stem cells was successfully implanted in a Baltimore man in Sweden (credit: Thomas Grosse/Harvard Bioscience)

Surgeons in Sweden have replaced the cancerous windpipe of a Maryland man with one made in a laboratory and seeded with the man’s cells.

The Y-shaped scaffold, fashioned from nano-size fibers of a type of plastic called PET that is commonly used in soda bottles, was seeded with stem cells from Christopher Lyles’ bone marrow. It was then placed in a bioreactor — a shoebox-size container holding the stem cells in solution.

After two days, it was installed in Mr. Lyles during an elaborate operation in which it was sutured to his throat and lungs. All told, the treatment cost about $450,000, Lyles said.