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	<title>Comments on: Toxic interaction in neurons that leads to dementia and ALS</title>
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	<link>http://www.kurzweilai.net/toxic-interaction-in-neurons-that-leads-to-dementia-and-als</link>
	<description>Accelerating Intelligence</description>
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		<title>By: Vern Westgate</title>
		<link>http://www.kurzweilai.net/toxic-interaction-in-neurons-that-leads-to-dementia-and-als/comment-page-1#comment-76047</link>
		<dc:creator>Vern Westgate</dc:creator>
		<pubDate>Sat, 22 Dec 2012 00:15:27 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=174302#comment-76047</guid>
		<description>Some testing is being done, I understand, at Mass General Hospital and in Israel on using adult stem cells to combat or slow down ALS. I suspect we may find causes and cures at the DNA, mRNA, and protein level.</description>
		<content:encoded><![CDATA[<p>Some testing is being done, I understand, at Mass General Hospital and in Israel on using adult stem cells to combat or slow down ALS. I suspect we may find causes and cures at the DNA, mRNA, and protein level.</p>
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		<title>By: Nick Radonic</title>
		<link>http://www.kurzweilai.net/toxic-interaction-in-neurons-that-leads-to-dementia-and-als/comment-page-1#comment-70489</link>
		<dc:creator>Nick Radonic</dc:creator>
		<pubDate>Sat, 15 Dec 2012 00:04:19 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=174302#comment-70489</guid>
		<description>Are you just angry at the disease process and our limited understanding? Or is there a specific drug that you feel is being withheld?</description>
		<content:encoded><![CDATA[<p>Are you just angry at the disease process and our limited understanding? Or is there a specific drug that you feel is being withheld?</p>
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		<title>By: rkl</title>
		<link>http://www.kurzweilai.net/toxic-interaction-in-neurons-that-leads-to-dementia-and-als/comment-page-1#comment-68590</link>
		<dc:creator>rkl</dc:creator>
		<pubDate>Thu, 13 Dec 2012 04:38:43 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=174302#comment-68590</guid>
		<description>These people have nothing to lose. eventually they have a terrible almost non existence. Why can&#039;t we sign people up and at least try some experimental drugs to help them and cut through all the FDA crap. I am sick of watching my loved one rot away because of lawyers and buerocrats. I would sign a legal waver....we have nothing to lose at this point!!!!!!!!</description>
		<content:encoded><![CDATA[<p>These people have nothing to lose. eventually they have a terrible almost non existence. Why can&#8217;t we sign people up and at least try some experimental drugs to help them and cut through all the FDA crap. I am sick of watching my loved one rot away because of lawyers and buerocrats. I would sign a legal waver&#8230;.we have nothing to lose at this point!!!!!!!!</p>
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		<title>By: Laura Crouch</title>
		<link>http://www.kurzweilai.net/toxic-interaction-in-neurons-that-leads-to-dementia-and-als/comment-page-1#comment-68520</link>
		<dc:creator>Laura Crouch</dc:creator>
		<pubDate>Thu, 13 Dec 2012 02:44:22 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=174302#comment-68520</guid>
		<description>It always amazes me how complicated the brain is. Thanks to all the under- noted scientists that work in pure research so that the human condition can be improved.</description>
		<content:encoded><![CDATA[<p>It always amazes me how complicated the brain is. Thanks to all the under- noted scientists that work in pure research so that the human condition can be improved.</p>
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		<title>By: Gorden Russell</title>
		<link>http://www.kurzweilai.net/toxic-interaction-in-neurons-that-leads-to-dementia-and-als/comment-page-1#comment-68296</link>
		<dc:creator>Gorden Russell</dc:creator>
		<pubDate>Wed, 12 Dec 2012 18:39:12 +0000</pubDate>
		<guid isPermaLink="false">http://www.kurzweilai.net/?p=174302#comment-68296</guid>
		<description>&quot;We sought to investigate how TDP-43 regulates the levels of the protein progranulin, given that extreme progranulin levels at either end of the spectrum, too low or too high, can respectively lead to neurodegeneration or cancer...”

Let&#039;s wish them luck.  We all want them to manage these proteins like the little bear&#039;s porridge.</description>
		<content:encoded><![CDATA[<p>&#8220;We sought to investigate how TDP-43 regulates the levels of the protein progranulin, given that extreme progranulin levels at either end of the spectrum, too low or too high, can respectively lead to neurodegeneration or cancer&#8230;”</p>
<p>Let&#8217;s wish them luck.  We all want them to manage these proteins like the little bear&#8217;s porridge.</p>
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