Wrinkled cell nuclei may make us age

April 28, 2006 | Source: [email protected]

A new study shows that cells from people over the age of 80 tend to have specific problems with the nucleus. The elderly nucleus loses its pert, rounded shape and becomes warped and wrinkled.

The National Cancer Institute team suggests that healthy cells always make a trace amount of an aberrant form of lamin A protein, but that young cells can sense and eliminate it. Elderly cells, it seems, cannot.

Blocking production of this deviant protein corrected all the problems with the nucleus, suggesting that drugs might slow or stay some symptoms of aging.