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First complete pictures of cells’ DNA-copying machinery

Electron microscope images reveal that structure of DNA-copying protein complex differs from long-held textbook view
November 3, 2015

These cartoons show the old "textbook" view of the replisome, left, and the new view, right, revealed by electron micrograph images in the current study. Prior to this study, scientists believed the two polymerases (green) were located at the bottom (or back end) of the helicase (tan), adding complementary DNA strands to the split DNA to produce copies side by side. The new images reveal that one polymerase is located at the front end of the helicase. The scientists are conducting additional studies to explore the biological significance of this unexpected location. (credit: Brookhaven National Laboratory)

The first-ever electron microscope images of the protein complex that unwinds, splits, and copies double-stranded DNA reveal something rather different from the standard textbook view.

The images, created by scientists at the U.S. Department of Energy’s Brookhaven National Laboratory with partners from Stony Brook University and Rockefeller University, offer new insight into how this molecular machinery functions, including new possibilities about its role… read more

Engineers design enhanced magnetic protein nanoparticles to better track cells

November 3, 2015

ferritin

 

MIT engineers have designed magnetic protein nanoparticles that can be used to track cells or to monitor interactions within cells. The particles, described Monday (Nov. 2) in an open-access paper in Nature Communications, are an enhanced version of a naturally occurring, weakly magnetic protein called ferritin.

“We used the tools of protein engineering to try to boost the magnetic… read more

Semantic Scholar uses AI to transform scientific search for computer scientists

November 3, 2015

Semantic Search

The Allen Institute for Artificial Intelligence (AI2) launched Monday (Nov. 2) its free Semantic Scholar service, intended to allow scientific researchers to quickly cull through the millions of scientific papers published each year to find those most relevant to their work.

Semantic Scholar leverages AI2’s expertise in data mining, natural-language processing, and computer vision, according to according to Oren Etzioni, PhD, CEO at… read more

Just one junk-food snack triggers signals of metabolic syndrome

Metabolic syndrome is associated with the risk of developing cardiovascular disease and diabetes
November 3, 2015

(credit: iStock)

Just one high-calorie milkshake was enough to make metabolic syndrome worse for some people. And overindulgence in just a single meal or snack (especially junk food) is enough to trigger the beginnings of metabolic syndrome, which is associated with the risk of developing cardiovascular disease and diabetes (obesity around the waist and trunk is the main sign).

That finding… read more

China plans world’s largest supercollider

CERN also planning High-Luminosity LHC upgrade for 2025
November 2, 2015

large hadron collider ft

Chinese scientists are completing plans for the Circular Electron Positron Collider (CEPC), a supergiant particle collider. With a circumference of 80 kilometers (50 miles) when built, it will be at least twice the size of the world’s current leading collider, the Large Hadron Collider at CERN, outside Geneva, according to the Institute of High Energy Physics in Beijing. Work on the collider is expect to start in 2020.… read more

Massive supercomputer simulation models universe from near birth until today

One of the largest cosmological simulations ever run
November 2, 2015

Galaxies have halos surrounding them, which may be composed of both dark and regular matter. This image shows a substructure within a halo in the Q Continuum simulation, with "subhalos" marked in different colors. (credit: Heitmann et al.)

The Q Continuum simulation, one of the largest cosmological simulations ever performed, has modeled the evolution of the universe from just 50 million years after the Big Bang to the present day.

DOE’s Argonne National Laborator led the simulation on the Titan supercomputer at DOE’s Oak Ridge National Laboratory.

Over the course of 13.8 billion years, the matter in the universe clumped… read more

Single-agent phototherapy system diagnoses and kills cancer cells

November 2, 2015

Phototherapy-System ft

Researchers at Oregon State University have announced a new single-agent phototherapy (light-based) approach to combating cancer, using a single chemical compound (SiNc-PNP), for both diagnosis and treatment.

The compound makes cancer cells glow when exposed to near-infrared light so a surgeon can identify the cancer. The compound includes a copolymer called PEG-PCL as the biodegradable carrier. The carrier causes the silicon naphthalocyanine to accumulate selectively in cancer… read more

How to build a full-scale quantum computer in silicon

The key is scalable error correction
November 2, 2015

2D donor qubit-array-ft

A new 3D silicon-chip architecture based on single-atom quantum bits has been designed by researchers at UNSW Australia (The University of New South Wales) and the University of Melbourne.

The use of silicon makes it compatible with existing atomic-scale fabrication techniques, providing a way to build a large-scale quantum computer.**

The scientists and engineers from the Australian Research Council Centre of Excellenceread more

Is this the ‘ultimate’ battery?

October 30, 2015

False-colour microscopic view of a reduced graphene oxide electrode (black, centre), which hosts the large (on the order of 20 micrometers) lithium hydroxide particles (pink) that form when a lithium-oxygen battery discharges (credit: T Liu et al./Science)

University of Cambridge scientists have developed a working laboratory demonstrator of a lithium-oxygen battery that has very high energy density (storage capacity per unit volume), is more than 90% efficient, and can be recharged more than 2000 times (so far), showing how several of the problems holding back the development of more powerful batteries could be solved.

Lithium-oxygen (lithium-air) batteries have been touted as the… read more

Flexible phototransistor is world’s fastest, most sensitive

May dramatically improve performance of cameras and other light-capturing devices
October 30, 2015

Developed by UW-Madison electrical engineers, this unique phototransistor is flexible, yet faster and more responsive than any similar phototransistor in the world (credit: Jung-Hun Seo)

University of Wisconsin-Madison (UW) electrical engineers have created the fastest, most responsive flexible silicon phototransistor ever made, inspired by mammals’ eyes.

Phototransistors (an advanced type of photodetector) convert light to electricity. They are widely used in products ranging from digital cameras, night-vision goggles, and smoke detectors to surveillance systems and satellites.

Developed by UW-Madison collaborators Zhenqiang “Jack” Ma, professor of electrical andread more

Long-term aerobic exercise prevents age-related brain deterioration

October 30, 2015

age-related changes ft

A study of the brains of mice shows that structural deterioration associated with old age can be prevented by long-term aerobic exercise starting in mid-life, according to the authors of an open-access paper in the journal PLOS Biology yesterday (October 29).

Old age is the major risk factor for Alzheimer’s disease, like many other diseases, as the authors at The Jackson Laboratory in Bar Harbor, Maine,… read more

Sleep disruptions similar to jet lag linked to memory and learning problems

Add good sleep habits to regular exercise and a healthy diet to maximize good memory, scientists advise
October 29, 2015

(credit: iStock)

Chemical changes in brain cells caused by disturbances in the body’s day-night cycle may lead to the learning and memory loss associated with Alzheimer’s disease, according to a University of California, Irvine (UCI) study.

People with Alzheimer’s often have problems with sleeping or may experience changes in their slumber schedule. Scientists do not completely understand why these disturbances occur.

“The issue is whether poor sleep accelerates… read more

MOTOBOT: the first autonomous motorcycle-riding humanoid robot

Cooler than Terminator and Robocop
October 29, 2015

MOTOBOT Ver. 1 (credit: Yamaha)

Yamaha introduced MOTOBOT Ver.1, the first autonomous motorcycle-riding humanoid robot, at the Tokyo Motor Show Wednesday (Oct. 28). A fusion of Yamaha’s motorcycle (an unmodified Yamaha YZF-R1M) and robotics technology, the future Motobot robot will ride an unmodified motorcycle on a racetrack at more than 200 km/h (124 mph), Yamaha says.

“We want to apply the fundamental technology and know-how gained in the process of this challenge… read more

This robot will out-walk and out-run you one day

Human-like “spring-mass” design may lead to walking-running robot soldiers, fire fighters, factory workers, and home servants of the near future.
October 29, 2015

ATRIAS

Imagine robots that can walk and run like humans — or better than humans. Engineers at Oregon State University (OSU) and Technische Universitat Munchen may have achieved a major step in that direction with their “spring-mass” implementation of human and animal walking dynamics, allowing robots to maintain balance and efficiency of motion in difficult environments.

Studies done with OSU’s ATRIAS robot model, which… read more

Controlling acoustic properties with algorithms and computational methods

October 28, 2015

A “zoolophone” with animal shapes automatically created using a computer algorithm. The tone of each key is comparable to those of professionally made instruments as a demonstration of an  algorithm for computationally designing an object's vibrational properties and sounds. (credit: Columbia Engineering)

Computer scientists at Columbia Engineering, Harvard, and MIT have demonstrated that acoustic properties — both sound and vibration — can be controlled by 3D-printing specific shapes.

They designed an optimization algorithm and used computational methods and digital fabrication to alter the shape of 2D and 3D objects, creating what looks to be a simple children’s musical instrument — a xylophone with keys in the shape of zoo animals.… read more

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Latest blog posts

Celebrating the 10 Year Anniversary of book The Singularity Is Near

October 6, 2015

anniversary - A5

Dear readers,

This month celebrates the 10 year anniversary of the classic book The Singularity Is Near, written by Ray Kurzweil, published in September 2005.

In the decade since its publication, we’ve witnessed an explosion of breakthroughs in genetic engineering, medical regeneration of the human body, autonomous robotics, computing power, and renewable energy. Advanced sensor arrays and internet meshes are uniting all people and things within the interconnected… read more

Should humans be able to marry robots?

Are you robophobic?
August 12, 2015 by Amara D. Angelica

(credit: AMC)

The Supreme Court’s recent 5–4 decision in Obergefell v. Hodges legalizing same-sex marriage raises the interesting question: what’s next on the “slippery slope”? Robot-human marriages? Robot-robot marriages?

Why yes, predicts on Slate.

“There has recently been a burst of cogent accounts of human-robot sex and love in popular culture: Her and Ex Machina, the AMC drama series Humans, and the novel … read more

Why we really should ban autonomous weapons: a response

By Stuart Russell, Max Tegmark & Toby Walsh
August 10, 2015

President Richard Nixon (seen here during his historical meeting with Chinese leader Mao Zedong) argued that a ban on biological weapons would strengthen U.S. national security (credit: White House Photo Office)

We welcome Sam Wallace’s contribution to the discussion on a proposed ban on offensive autonomous weapons. This is a complex issue and there are interesting arguments on both sides that need to be weighed up carefully.

His article, written as a response to an open letter signed by over 2500 AI and robotics researchers, begins with the claim that such a ban is as “unrealistic… read more

The proposed ban on offensive autonomous weapons is unrealistic and dangerous

So says former U.S. Army officer and autonomous weapons expert Sam Wallace
August 5, 2015

From Call of Duty Black Ops 2 (credit: Activision Publishing)

The open letter from the Future of Life Institute (FLI) calling for a “ban on offensive autonomous weapons” is as unrealistic as the broad relinquishment of nuclear weapons would have been at the height of the cold war.

A treaty or international agreement banning the development of artificially intelligent robotic drones for military use would not be effective. It would be impossible to completely stop nations from… read more

Ask Ray | Renowned economist and author George Gilder’s new information theory of money

August 4, 2015

money - A3

Dear readers,

Renowned economist, activist, author, and my long time friend, George Gilder has come out with his latest book titled A 21st Century Case for Gold: A New Information Theory of Money.

He makes a new case for understanding why the United States economy has had trouble rebounding.

George Gilder explains this is due to a misunderstanding of what monetary policy can do, and the creation of… read more

Ask Ray | My middle school supported my interest in Ray Kurzweil’s work and teen trip to Singularity University

July 25, 2015

Arduino is an open source electronics platform based on easy to use hardware and software. It's intended for anyone making interactive projects. -- credit | Arduino

Dear Dr. Kurzweil,

My middle school was supportive of my interest in your work and my visit to your school Singularity University, as a teenager, to see the program you founded for exploring the future.

Thank you for inviting me, and for the opportunity to audit two days there. I had a fantastic time. Everyone at Singularity University was very nice and welcoming.

My favorite presentation was… read more

Hit TV show Humans on intelligent android servants

June 26, 2015 by Amara D. Angelica

HUMANS robots

A reminder: HUMANS premieres in the U.S. Sunday June 28, 2015 at 9PM EDT on AMC.

This eight-part drama series takes place in a parallel present, featuring the Synth — a highly developed, artificially intelligent android servant.

Having seen the first two episodes, I’m totally hooked. I found the show surprisingly believable. It (almost) fills the void left after Almost Human and Fringe.

The Atlanticread more

Ask Ray | Health technologies to support sleep apnea and snoring

June 22, 2015

credit | Airing

Dear readers,

Obstructive sleep apnea is a very common sleep disorder caused by periodic obstruction of the upper airway. A sleep apnea is literally a pause in breathing. It can happen many times each hour while the individual is asleep. It leads to reduced oxygen saturation and is a risk factor for heart disease.

Most sufferers are unaware that they have this syndrome. It is often first noticed… read more

Ask Ray | Future artificial intelligence acceptance or fear

May 5, 2015

The future of the human experience connects people and data. -- credit | iStock

Dear Ray,

Take a look at this article in Russia Today. In our film The Singularity Is Near — that we produced and wrote together — the “Jerry Garcia” character is wailing about cyberconscious citizenship.

I’m not sure what part of “we are merging together” these people don’t get! To me it is as obvious as the nose on my face. Funny how well we predicted and depicted… read more

Internet radio without the web

High quality music service on Kickstarter to offer 40 million songs, using caching instead of streaming
March 23, 2015 by Amara D. Angelica

AIVVY headset (credit: AIVVY)

I got this post today from Martine Rothblatt, PhD, CEO of United Therapeutics:

” I am very excited. March 24, 2015 is Kickstarter launch for AIVVY — CEO in pictures showing me smartphone control interface.  I’m in! It is best audio streaming interface I’ve ever experienced, and compatible with Sirius XM.

“Lets you run/bike and listen to great audio without getting RF power across your skin from cellular… read more

Transhumanist position on human germline genetic modification

March 22, 2015 by James Hughes

(credit: pixabay)

Recently a group of scientists and an industry group have issued statements calling for a moratorium on human heritable or germline genetic modifications (see herehere and here), now that we have the powerful CRISPR technique to pursue such modifications.

These statements have been greeted rapturously by bioconservatives, who want to see a global ban on germline and enhancement genetic therapies.

Of… read more

Ask Ray | Futurist Martine Rothblatt, PhD discusses cyber consciousness

March 19, 2015

brain - A1

Dear readers,

I want to recommend this article in USA Today profiling Martine Rothblatt, PhD’s keynote at South by Southwest.

USA Today | Sirius founder envisions world of cyber clones, tech med

Her talk featured a roundup of concepts about the future of the human brain and the potential for people to interact through virtual avatars and recreations of an individual.

USA Todayread more

Ray Kurzweil music technology breakthroughs – inside story

Background on Kurzweil's Technical Grammy Award
February 8, 2015 by Amara D. Angelica

Kurzweil 250 prototype boards (credit: Kurzweil Music Systems/Young Chang)

In Fall 1983, visitors crammed into a packed demo on the fifth floor of the New York Hilton Hotel during the New York AES convention and marveled at the Kurzweil K250, noted Electronic Musician magazine in its March 2015 issue.

“The first ROM-based sampling keyboard to successfully reproduce the full complexity of acoustic instruments, the 250 offered natural-sounding pianos, thick drums, lush strings, and more, and its… read more

Ray Kurzweil receives 2015 Technical Grammy Award for outstanding achievements in music technology

February 7, 2015

Grammy Awards - 57th - logo

Ray Kurzweil received the 2015 Technical Grammy Award on February 7, 2015 for his outstanding achievements in the field of music technology.

One of his primary inventions paved the way for re-creating acoustic instruments with electronic equivalents.

The Technical Grammy Award is a Special Merit Award presented by vote of the National Academy of Recording Arts & Sciences Trustees, for contributions of outstanding technical significance to the recording… read more

Machine Cognition and AI Ethics at AAAI 2015

February 4, 2015 by Melanie Swan

robot brain chip

The AAAI’s Twenty-Ninth Conference on Artificial Intelligence was held January 25–30, 2015 in Austin, Texas. Machine cognition was an important focal area covered in two workshops on AI and Ethics, and Beyond the Turing Test, and in a special track on Cognitive Systems.

Some of the most interesting emergent themes are discussed in this article.

Computational Ethicsread more

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