24 results

[ News ] How to detect early signs of Alzheimer’s with a simple eye exam before symptoms appear

July 12, 2016

retina - red wavelength ft

University of Minnesota (UMN) scientists and associates have developed new technology that can detect signs of Alzheimer’s before the onset of symptoms — early enough to give drugs a chance to work — in mice and humans by simply examining the back of their eyes.

Looking at Alzheimer’s effects through the eye is a key advantage of the new technology. “The retina of the eye is not just ‘connected’… read more

[ News ] Deep-brain imaging reveals which nearly identical neurons are associated with specific behaviors

January 30, 2015

Integration of the miniepifluorescence microscope with the microendoscope for deep-brain imaging of LH GABAergic neurons expressing GCaMP6m (credit: Joshua H. Jennings et al./Cell)

Researchers at the UNC School of Medicine have used new deep-brain imaging techniques to link the activity of individual, genetically similar neurons to particular behaviors of freely moving mice.

For the first time ever, scientists watched as one neuron was activated when a mouse searched for food while a nearly identical neuron next to it remained inactive; instead, the second neuron only became activated when the mouse began… read more

[ News ] Robot uses steerable needles to treat brain clots

August 9, 2013


Vanderbilt University researchers are developing an image-guided robotic surgical system to remove blood clots in the brain.

It uses steerable needles about the size of those used for biopsies to penetrate the brain with minimal damage and suction away the blood clot that has formed.

The odds of a person getting an intracerebral hemorrhage are one in 50 over his or her lifetime. When… read more

[ News ] Nanotools for neuroscience and brain activity mapping

March 25, 2013


“Neuroscience — one of the greatest challenges facing science and engineering — is at a crossroads. …There exist few general theories or principles that explain brain function [due partly to] limitations in current methodologies,” say neuroscientists in a new ACS Nano open-access paper, “Nanotools for Neuroscience and Brain Activity Mapping.”

Traditional neurophysiological approaches record the activities of one neuron or a few neurons at a time. Neurochemical… read more

[ News ] A high-resolution endoscope as thin as a human hair

March 13, 2013


Engineers at Stanford University have developed a prototype single-fiber endoscope that is as thin as a human hair, with a resolution four times better than previous devices of similar design.

The “micro-endoscope” is a significant step forward in high-resolution, minimally invasive bioimaging, with potential applications in research and clinical practice. Micro-endoscopy could enable new methods in diverse fields ranging from study of the brain to early cancer… read more

[ News ] New imaging technologies transforming medicine

October 9, 2012


A new wave of imaging technologies is transforming the practice of medicine, The New York Times reports, to give doctors an instantaneous diagnosis, as well as inexpensive systems, often based on smartphones, that can extend advanced imaging technologies to the entire world.

Driven largely by the falling cost of computing and the increasing availability of other miniaturization technologies, including nanotechnology, they include:

  • Endoscopes that use

read more

[ News ] Wireless power system replaces batteries in implants

September 5, 2012

High-frequency wireless power transmission to a device in the human heart. Red indicates greatest power; blue is least. (Credit: John Ho, Stanford Engineering)

Stanford University engineers have demonstrated the feasibility of a super-small, implantable cardiac device that gets its power from radio waves transmitted from a small transmitter on the surface of the body.

This is an impressive achievement that may lead to replacing bulky batteries in implants. That means the implants can be further miniaturized, while eliminating surgery to replace or charge batteries (or require a wired connection outside the body).… read more

[ News ] A nanowire endoscope for imaging inside a single cell

December 22, 2011

Endoscope Sensing

An endoscope that can provide high-resolution optical images of the interior of a single living cell, or precisely deliver genes, proteins, therapeutic drugs or other cargo without injuring or damaging the cell, has been developed by researchers from Berkeley Lab and the University of California (UC) Berkeley.

The researchers  attached a tin-oxide nanowire waveguide to the tapered end of an optical fiber to create a novel endoscope system. Light… read more

[ News ] ‘Fantastic Voyage’ through the digestive track

December 19, 2011

Illustration of an endoscopic capsule, propelled by magnetic swimming tails (1). The capsule payload is a micro-camera (5) and tool for biopsy (4). The power source is non-magnetic batteries (2). There is also electronics for command and control and communication (7), housing (8), and an antenna (3) for the RF transceiver. (Credit: Gábor Kósa et al.)

In a scene out of the movie Fantastic Voyage, Dr. Gabor Kosa of Tel Aviv University has developed a wireless “capsule endoscope” that can be remotely steered through the digestive tract to detect problem like hidden tumors or wounds, or allow for treatments such as biopsies or local drug delivery.

However, rather than miniaturized people (the technology is not quite there yet), the device is remotely… read more

[ News ] New high-speed 3-D imaging system holds potential for improved cancer screening

August 1, 2011

This is a 3-D OCT volumetric data set from an excised human colon specimen. (A) En face view showing regular organization of normal colon. (B and C) Cross-sectional views along two different directions showing sub-surface features. Two cross-sections are shown as examples, however multiple cross-sectional views can be extracted from the 3-D OCT data. Scale bar: 500um (credit: Massachusetts Institute of Technology

Researchers at MIT have developed a new imaging system that enables high-speed, 3-D imaging of microscopic pre-cancerous changes in the esophagus or colon.

The new endoscopic optical coherence tomography (OCT) imaging system works at record speeds, capturing data at a rate of 980 frames (equivalent to 480,000 axial scans) per second — nearly 10 times faster than previous devices — while imaging microscopic features… read more

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