Next-generation-sequencing report published
October 21, 2012
The Association for Molecular Pathology (AMP) has published the report of the Whole Genome Analysis (WGA) Working Group of the AMP Clinical Practice Committee in the November 2012 issue of The Journal of Molecular Diagnostics (JMD).
Titled Opportunities and Challenges Associated with Clinical Diagnostic Genome Sequencing, the open-access report provides an overview of the landscape of next generation sequencing (NGS) technology, its clinical relevance, and its impact on improving patient care.
This report illuminates the opportunities and challenges associated with clinical diagnostic genome sequencing. It reviews the rapidly evolving technologies; provides application examples; discuss aspects of clinical utility, ethics, and consent; and addresses the analytic, postanalytic, and professional implications.
- Iris Schrijver, Nazneen Aziz, Daniel H. Farkas, Manohar Furtado, Andrea Ferreira Gonzalez, Timothy C. Greiner, Wayne W. Grody, Tina Hambuch, Lisa Kalman, Jeffrey A. Kant, Roger D. Klein, Debra G.B. Leonard, Ira M. Lubin, Rong Mao, Narasimhan Nagan, Victoria M. Pratt, Mark E. Sobel, Karl V. Voelkerding, Jane S. Gibson, Opportunities and Clinical Challenges Associated with Clinical Diagnostic Genome Sequencing, The Journal of Molecular Diagnostics, 2012, DOI: 10.1016/j.jmoldx.2012.04.006 (open access)