Powerful Molecular Motor Permits Speedy Assembly of Viruses

October 30, 2007 | Source: PhysOrg.com

A team of physicists has shown that a tiny viral motor generates twice as much power, relative to its size, as an automobile engine. The finding explains why even very large viruses can self-assemble so rapidly.

The researchers say that their work could ultimately lead to better ways of designing antiviral medications. Drugs that target the DNA-packaging process could block the infection cycle by preventing viral assembly.

Such drugs could also interfere with the ability of the virus to inject its DNA into the cells it infects because injection is facilitated by the high pressure at which the genetic material is packaged within the virus’ outer shell, or capsid.