Smart Rat ‘Hobbie-J’ Produced By Over-expressing A Gene That Helps Brain Cells Communicate
October 20, 2009 | Source: ScienceDaily
Over-expressing the NR2B gene lets brain cells communicate just a fraction of a second longer and makes a smarter rat, report researchers from the Medical College of Georgia and East China Normal University.
The finding further validates NR2B as a drug target for improving memory in healthy individuals as those with Alzheimer’s or mild dementia, the scientists say.
NR2B is a subunit of NMBA receptors, which are like small pores on brain cells that let in electrically-charged ions that increase the activity and communication of neurons.