Toxic sensor chip combines electronics with living cell
June 11, 2003 | Source: KurzweilAI
University of California, Berkeley, researchers have found a way to tap into the telltale electrical signals that mark cell death, opening the door to the creation of a “canary on a chip” that can be used to sound the alarm of a biochemical attack or test drug toxicity on human tissue.
The researchers used a microchip to electrically determine cell viability by detecting changes in the electrical resistance of a cell membrane within milliseconds after it is exposed to a toxic agent. They found that after a cell is exposed to a toxin, its electrical resistance experiences a quick spike before dropping dramatically when it dies.