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Stem Cells Changed Into Precursors For Sperm, Eggs

October 29, 2009

Stanford University School of Medicine. researchers have devised a way to efficiently coax human embryonic stem cells to become human germ cells — the precursors of egg and sperm cells — in the laboratory.

Unlike previous research, which yielded primarily immature germ cells, the cells in this study functioned well enough to generate sperm cells.

Stem cells contain immortal DNA

July 3, 2006

Scientists at the Pasteur Institute have shown for the first time the mechanism that adult muscle stem cells use to protect their DNA from mutations: they retain the original DNA strands.

Understanding this has important implications for cancer research, the study of gene regulation, and ultimately growing stem cells of therapeutic potential in the laboratory.

Stem cells ‘could restore vision’

October 27, 2004

University of Toronto scientists found that human retinal stem cells regenerated when they were transplanted into the eyes of mice and chicks.

These stem cells could eventually be used to restore normal vision in people with sight problems, the researchers say.

Stem cells develop into kidney cells

July 25, 2001

Adult stem cells taken from bone marrow can develop into kidney cells, British scientists have discovered.
Bone marrow stem cells, which are immature blood cells, have already been shown to transform into liver, nerve and muscle cells.

Both adult and embryonic stem cells have enormous medical potential due to their ability to mature into a wide range of different tissues, which could then be transplanted. However, ethical considerations have… read more

Stem cells found in adults may repair nerves

February 18, 2004

Researchers have learned that some nerves, even nerves in parts of the brain, can regenerate or be replaced, using stem cells. However, the pace of stem-cell repairs in humans is slow. And in some cases, they can even impede healing.

“We’re studying ways that this process is regulated to see if it can be manipulated to promote healing,” according to Dr. Philip Horner, an assistant professor in the Department… read more

Stem cells from cloned embryos keep genetic integrity

January 17, 2006

Stem cells derived from cloned embryos appear genetically identical to those created by fertilisation in mice, researchers at the Whitehead Institute for Biomedical Research report.

The results of the new study — which examined gene expression patterns in the stem cells — suggest that there is no subset of genes that is universally activated or disabled in cloned stem cells as compared with their normal stem cell counterparts.… read more

Stem Cells from Hair Follicles May Help ‘Grow’ New Blood Vessels

March 31, 2008
Smooth muscle progenitor cell derived from a hair follicle

University of Buffalo researchers have found that stem cells isolated from sheep and human hair follicles contain the smooth muscle cells that grow new blood vessels.

The smooth muscle progenitor cells are capable of dilating and constricting, which are critical properties for cardiovascular tissue engineering.

University of Buffalo News Release

Stem cells grown into tissues

October 28, 2003

MIT scientists today reported the first known success in using human embryonic stem cells to grow primitive versions of human organs and tissues. They say this represents a promising step toward the development of lab-engineered tissues that could one day eliminate some organ shortages.

The researchers, led by Robert Langer, created structures resembling young cartilage, liver, and neural tissues by growing cells on biodegradable polymer scaffolds — spongelike structures… read more

Stem Cells Help More Mice Walk

September 19, 2005

Injections of human stem cells in mice seem to directly repair some of the damage caused by spinal cord injury, going beyond previous research by repairing myelin cells, which create the biological insulation that nerve fibers need to communicate.

A number of neurological diseases, such as multiple sclerosis, involve loss of that insulation.

Stem cells improve visual function in blind mice

October 2, 2012

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An experimental treatment for blindness, developed from a patient’s skin cells, improved the vision of blind mice in a study conducted by Columbia ophthalmologists and stem cell researchers.

The findings suggest that induced pluripotent stem (iPS) cells — which are derived from adult human skin cells but have embryonic properties — could soon be used to restore vision in people with macular degeneration and other… read more

Stem cells join muscle, spinal cord cells in ‘human-on-a-chip’ simulation

November 24, 2011

University of Central Florida researchers, for the first time, have used stem cells to grow neuromuscular junctions between human muscle cells and human spinal cord cells, the key connectors used by the brain to communicate and control muscles in the body.

.The National Institutes of Health (NIH), the Defense Advanced Research Projects Agency (DARPA), and the Federal Drug Administration (FDA) have recently launched an ambitious… read more

Stem Cells Made From ‘Dead’ Human Embryo

September 26, 2006

Scientists say they have created a stem cell line from a human embryo that had stopped developing naturally, and so was considered dead. Using such embryos might ease ethical concerns about creating such cells, they suggested.

Stem cells made to mimic disease

April 8, 2008

Harvard Medical School and Nottingham scientists have taken skin cells from patients with eight different diseases and turned them into stem cells, moving one step closer to using stem cells from patients themselves to treat disease.

Stem Cells May Be Key to Cancer

February 21, 2006

At the heart of every tumor, some researchers believe, lie a handful of aberrant stem cells that maintain the malignant tissue.

The idea, if right, could explain why tumors often regenerate even after being almost destroyed by anticancer drugs. It also points to a different strategy for developing anticancer drugs, suggesting they should be selected for lethality to cancer stem cells and not, as at present, for their ability… read more

Stem cells may mend a broken heart

July 30, 2007

Stem cells may help repair damaged tissue after a heart attack, according to Harvard Medical School researchers.

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