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Live fast, die old

June 2, 2004

Mice with sky-high metabolic rates live far longer than their sluggish cousins, UK researchers have found, raising the prospect that human lifespan might be lengthened with metabolism-boosting drugs.

The group of animals with the highest metabolic rates lived over a third longer than the group with the lowest rates, they found, and had metabolisms that ran about 30% faster. If the same is true in humans, this means that… read more

Genetically-modified virus explodes cancer cells

June 2, 2004

A genetically-modified virus that exploits the selfish behaviour of cancer cells may offer a powerful and selective way of killing tumors.

Deleting a key gene from the virus enabled it to infect and burst cancer cells while leaving normal tissues unharmed.

The UK researchers deleted one such gene in an adenovirus. This meant that the virus was immediately detected by normal cells and was unable to spread. But… read more

This Is Your Brain on Drugs

June 1, 2004

Scientists are developing technology to peer into the brains of people taking antidepressants, hoping to cut down on the arduous process of evaluating the drugs.

Aspect Medical Systems has developed a system to do that based on the EEG, which records the firing of brain cells in the frontal lobe, blood flow and other activity. It uses a disposable strip of electrodes that affixes to the forehead and feeds… read more

Interview: Abrupt Climate Change, the Pentagon, and The Day After Tomorrow

June 1, 2004

Doug Randall, who co-authored “the Pentagon study” on abrupt climate change, has commented on the “Day After Tomorrow film.

“The timeframe is definitely exaggerated, but the premise is one of the real issues of our day,” he said. “The danger signs come from the world of science and have to do with things like salinity of the Atlantic Ocean and the thermohaline conveyor. Signs that point to big shifts… read more

The Little Engine That Could

June 1, 2004

Robert X. Cringley predicts the coming demise of the landline telco monopolies from VoIP (voice over Internet) and Linux running on the latest generation of WiFi routers connected to local subscribers via a mesh network.

“The result is a system with economics with which a traditional local phone company simply can’t compete,” he says.

Puckish robots pull together

June 1, 2004

The frictionless conditions of space are being simulated by air-hockey tables, as a new generation of intelligent robots is trained to build space stations and solar arrays.

The work demonstrates how teams of mobile, communicating robots can perform complex tasks: for example, they can collaborate to push objects over a surface. This is reminiscent of the way ants show group intelligence when carrying out collective tasks such as foraging.… read more

Disaster Movie Makes Waves

June 1, 2004

The Day After Tomorrow eco-disaster film’s premise that human activity could trigger a sudden ice age is unlikely, say scientists.

‘Earthshine’ fall heats global warming debate

June 1, 2004

A new study of earthshine, the sunlight reflected back onto the Moon from our planet, suggests that falling cloud cover could explain the warming of the Earth’s lower atmosphere seen over the last 20 years.

The decline suggests fewer clouds, which reflect sunlight, and therefore that more sunlight has been making it into the lower atmosphere (troposphere).

The idea presents a controversial alternative to most scientists’ prime suspect… read more

Mathematical model for cell signaling developed

May 28, 2004

A new mathematical model will help researchers understand “cell signaling” and learn how single atoms travel along the circuitous pathways in a cell. It may allow researchers to study biochemistry at the atomic level.

The model is a new approach to look at percolation — the flow of a liquid or small particle through a porous material. In the simulation, materials pass through fields of complex, three-dimensional shapes.… read more

Nanoparticles illuminate brain tumors for days under MRI

May 28, 2004

Iron oxide nanoparticle ferumoxtran-10, sized as small as a virus, can outline brain tumors under magnetic resonance imaging and other lesions in the brain that may otherwise have gone unnoticed, according to a study published in the journal Neuropathology and Applied Neurobiology.

The studies’ findings have the potential to assist image-guided brain surgery and improve diagnosis of lesions caused by multiple sclerosis, stroke and other neurological disorders, in addition… read more

Pharmacogenomics could replace ‘trial-and-error’ with science from the human genome

May 28, 2004

Pharmacogenomics, which bases the choice of medications and their dosages on the patient’s specific genetic makeup (“individualized medicine”) could lower the cost of health care by decreasing the occurrence of adverse drug effects and increasing the probability of successful therapy, investigators at St. Jude Children’s Research Hospital report in the May 27 issue of Nature.

The key to pharmacogenomics is its ability to predict how a patient will respond… read more

Small world networks key to memory

May 28, 2004

Working memory appears to be based on simple networks of “small world” (maximally connected) neurons in the prefrontal cortex that participate in self-sustaining bursts of electrical activity.

Northwestern University researchers have created a model of these networks, using simple neurons that when activated would activate their neighbours for a brief period: an activating pulse travelled through the network and then disappeared at the fringes. They then added shortcuts to… read more

CIA’s spy tools make Maxwell Smart’s look like toys

May 28, 2004

The CIA’s future information analysis technologies will make Google look like a toy. In-Q-Tel’s investments provide a glimpse of what they might do.

  • Tacit Knowledge Systems’ software could facilitate information sharing by scanning every agent’s outgoing e-mail, looking for clusters of words that tell the system what and who each agent seems to know. And MetaCarta can figure out where the information is about.
  • PiXlogic can
  • read more

    MOVIE REVIEW — ‘THE DAY AFTER TOMORROW’

    May 28, 2004

    Smart hero. Dumb officials. Huge sheet of ice. The Day After Tomorrow,” a two-hour $125 million disaster movie opening nationwide on Friday, proposes an apocalypse that covers the Northern Hemisphere in a sheet of ice and snow.

    Some environmental groups are using the release of “The Day After Tomorrow” to raise awareness of global warming but agree that the conditions could take hundreds of years to develop.

    Looking back into the future

    May 28, 2004

    Tales of Future Past is a collection, with commentary, of early magazine covers and other speculative illustrations — portraying life on distant planets and in the distant future…like the 1970s.

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